Development of the Mouse External Genitalia: Unique Model of Organogenesis

  • Kentaro Suzuki
  • Kohei Shiota
  • Yanding Zhang
  • Lei Lei
  • Gen Yamada
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 545)


The mammalian external genitalia develop highly specialized structures suitable for efficient internal fertilization. The advent of molecular developmental biology has led to the accumulation of large amounts of data regarding mammalian organogenesis. However, there is not much research on the development of external genitalia (Cunha and Lung, 1979, Dolle et al., 1991; Kondo et al., 1997; Warot et al., 1997). Even recent molecular analyses of this organ utilize embryological observations often dated several decades ago.


External Genitalia Limb Development Ventral Midline Urogenital Sinus Apical Ectodermal Ridge 
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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Kentaro Suzuki
    • 1
  • Kohei Shiota
    • 2
  • Yanding Zhang
    • 3
  • Lei Lei
    • 1
  • Gen Yamada
    • 1
  1. 1.Center for Animal Resources and Development (CARD) and Graduate School of Molecular Genomic PharmacyKumamoto UniversityKumamotoJapan
  2. 2.Congenital Anomaly Research Center and Department of Anatomy and Developmental Biology, Graduate School of MedicineKyoto UniversityKyotoJapan
  3. 3.College of BioengineeringFujian Teachers University, FuzhouFujianChina

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