Antibiotics for Acute Otitis Media in the Era of Antibiotic Resistance—What are the Choices?
Otitis media is the most common respiratory tract infection of infancy and early childhood that is managed with antibacterial agents. The bacteriology of otitis media in children is well-known and comprises three main pathogens: Streptococcus pneumoniae, nontypable Haemophilus influenzae, and to a lesser extent, Moraxella catarrhalis (Dagan and Leibovitz, 2002). In patients in whom treatment is warranted, the role of antibiotics is to eradicate the causative organism from the middle ear cavity. To achieve this goal, the antibiotic must be active in vitro against the targeted organisms and must penetrate the middle ear cavity in sufficient concentrations.
KeywordsPlacebo Penicillin Ampicillin Erythromycin Cephalosporin
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