Globally, malaria is the most important parasite infection in terms of the geographic distribution and its effect on health and economic growth. Over a third of the world’s population live in malaria-endemic areas (Guerin et al., 2002), however the greatest burden on public health is in sub-Saharan Africa, where at least 90% of malarial infections and deaths in the world occur (Teklehaimanot and Snow, 2002), the latter almost entirely in children less than 5 years old. Each year, malaria results in an estimated 200–450 million cases of fever in children and over 0.5 million deaths (Snow et al., 1999). The burden of malaria is increasing, especially in sub-Saharan Africa, and this increase is mainly attributable to drug and insecticide resistance and social and environmental changes (Greenwood and Mutabingwa, 2002).
KeywordsSevere Malaria Cerebral Malaria African Child Severe Malarial Anemia Severe Falciparum Malaria
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