Scaling Up of Catalysts Discovered from Small-Scale Experiments

  • Maureen L. Bricker
  • Ralph D. Gillespie
  • Jennifer S. Holmgren
  • J. W. Adriaan Sachtler
  • Richard R. Willis

Abstract

The chemical industry faces a challenging business climate due to difficult economic conditions in much of the world, strong international competition, and worldwide environmental concern. In addition, innovation in this industry has slowed as catalyst and process technology has matured. The need for a methodology that can increase catalyst innovation while continuing to decrease cycle times has been recognized by the Council for Chemical Research (Catalysis Roadmap, Vision 2020) [1]. In the 1980s, the pharmaceutical industry faced similar circumstances. Downward pressure on drug prices became incompatible with the high cost of drug discovery. Combinatorial chemistry, based on advances in laboratory automation, high-throughput synthesis, and activity screening, allowed the pharmaceutical companies to break the innovation impasse [2, 3].

Keywords

Sulfide Steam Zeolite Hexane Toluene 

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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Maureen L. Bricker
    • 1
  • Ralph D. Gillespie
    • 1
  • Jennifer S. Holmgren
    • 1
  • J. W. Adriaan Sachtler
    • 1
  • Richard R. Willis
    • 1
  1. 1.UOP LLCDes PlainesUSA

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