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Pseudoallelism and Gene Evolution

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Genes, Development and Cancer

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Abstract

It is the purpose of this paper to consider some of the ways in which “pseudoalleles” (McClintock, 1944), or closely linked genes having similar effects, may provide clues to the mode of origin of new kinds of genes.Our underlying thesis will be that in those instances of pseudoallelism in which there is evidence for close functional similarity among the component genes we may come close to seeing the direct results of a process which produces new genes.

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Authors and Affiliations

  1. Kerckhoff Laboratories of Biology, California Institute of Technology, Pasadena, California, USA

    E. B. Lewis

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  1. E. B. Lewis
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Editors and Affiliations

  1. Program in Developmental Biology, The Hospital for Sick Children Research Institute, Toronto, Canada

    Howard D. Lipshitz (Senior Scientist and Head, Professor of Molecular and Medical Genetics, Canada Research Chair in Developmental Biology) (Senior Scientist and Head, Professor of Molecular and Medical Genetics, Canada Research Chair in Developmental Biology)

  2. University of Toronto, Toronto, Canada

    Howard D. Lipshitz (Senior Scientist and Head, Professor of Molecular and Medical Genetics, Canada Research Chair in Developmental Biology) (Senior Scientist and Head, Professor of Molecular and Medical Genetics, Canada Research Chair in Developmental Biology)

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© 2004 Springer Science+Business Media New York

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Lewis, E.B. (2004). Pseudoallelism and Gene Evolution. In: Lipshitz, H.D. (eds) Genes, Development and Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8981-9_7

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  • DOI: https://doi.org/10.1007/978-1-4419-8981-9_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4746-0

  • Online ISBN: 978-1-4419-8981-9

  • eBook Packages: Springer Book Archive

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