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Application of a Novel Protein Chip Mass Spectrometry Technology for the Identification of Bladder Cancer-Associated Biomarkers

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Bladder Disease, Part A

Abstract

The molecular heterogeneity of cancer suggests that simultaneous screening of a sample for different molecular markers is necessary in order to increase accuracy of cancer diagnosis. DNA chip technologies address this problem at the genomic level and provide accessibility to gene expression profiles.

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References

  1. Abbott A: A post-genomic challenge: learning to read patterns of protein synthesis. Nature, 402:715, 1999.

    Article  PubMed  CAS  Google Scholar 

  2. Banks RE, Dunn MJ, Forbes MA, Stanley A, Pappin D, Naven T, et al: The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis: Preliminary findings. Electrophoresis, 20:689, 1999.

    Article  PubMed  CAS  Google Scholar 

  3. Billed TM, Stults BT: Tryptic mapping of recombinant proteins by matrix-assisted laser/desorption ionization mass spectrometry. Anal Chem, 65:1709, 1993.

    Article  Google Scholar 

  4. Carr SA, Hemling ME, Bean MF, Roberts GD: Integration of mass spectrometry in analytical biotechnology. Anal Chem, 63:2802, 1991.

    Article  PubMed  CAS  Google Scholar 

  5. Carr SA, Annan RS: Overview of Peptide and Protein Analysis by Mass Spectrometry. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, editors. Current Protocols in Molecular Biology. New York: John Wiley & Sons Inc.; unit 10.21, pp. 10.21.1–10.21.27, 1998.

    Google Scholar 

  6. Clauser KR, Hall SC, Smith DM, Webb JW, Andrewes LE, Tran HM, et al: Rapid mass spectrometric peptide sequencing and mass matching for characterization of human melanoma proteins isolated by two-dimensional PAGE. Proc Natl Acad Sci USA, 92:5072, 1995.

    Article  PubMed  CAS  Google Scholar 

  7. Dogruel D, Williams P, Nelson RW: Rapid tryptic mapping using enzymatically-active mass spectrometer probe tips. Anal Chem, 67:4343, 1995.

    Article  PubMed  CAS  Google Scholar 

  8. Emmert-Buck MR, Bonner RF, Smith PD, Chuagui FR, Zhuang Z, Goldstein SR, et al: Laser capture microdissection. Science, 274:998, 1996.

    Article  PubMed  CAS  Google Scholar 

  9. Fenn JB, Mann M, Meng CK, Wong SF, Whitehouse CM: Electrospray ionization for the mass spectrometry of large biomolecules. Science, 246:64, 1989.

    Google Scholar 

  10. Grossman HB, Dinney CPN: Markers of bladder cancer: State of the art. Urol Oncol, 5:3, 2000.

    Article  PubMed  CAS  Google Scholar 

  11. Hillenkamp F, Karas M, Beavis RC, Chait BT: Matrix Assisted Laser Desorption Ionization Mass Spectrometry of biopolymers. Anal Chem, 63:1193, 1991.

    Article  Google Scholar 

  12. Hunt DF, Yates JR, Shabanowitzz J, Winston S, Hauer CR: Protein sequencing by tandem mass spectrometry. Proc Natl Acad Sci USA, 83:6233, 1986.

    Article  PubMed  CAS  Google Scholar 

  13. Hutchens TW, Yip TT: New desorption strategies for the mass spectrometric analysis of macromolecules. Rapid Commun Mass Spectrom, 7:576, 1993.

    Article  CAS  Google Scholar 

  14. Hutchens TW, Yip TT: Affinity Mass Spectrometry. Protein Sci, 2:92, 1993.

    Google Scholar 

  15. Israeli RS, Powell CT, Corr JG, Fair WR, Heston WDW: Expression of the prostate specific membrane antigen. Cancer Res, 54:1807, 1991.

    Google Scholar 

  16. Jensen ON, Podtelejnikov AV, Mann, M: Identification of the components of simple protein mixtures by high accuracy peptide mass mapping and database searching. Anal Chem, 69:4741, 1997.

    Article  PubMed  CAS  Google Scholar 

  17. Karas M, Bachmann D, Bahr U, Hillenkamp F: Matrix-assisted ultraviolet laser desorption of non-volatile compounds. Int J Mass Spectrom Ion Proc, 78:53, 1987.

    Article  CAS  Google Scholar 

  18. Karas M, Hillenkamp F: Laser desorption ionization of proteins with molecular mass exceeding 10000 daltons. Anal Chem, 60:2299, 1988.

    Article  PubMed  CAS  Google Scholar 

  19. Kaufmann R, Kirsch D, Spengler B: Sequencing of peptides in a time of flight MS: Evaluation of a post source decay following matrix-assisted laser desorption ionization (MALDI). Int J Mass Spectrom Ion Process, 131:355, 1994.

    Article  CAS  Google Scholar 

  20. Kaufmann R: Matrix-assisted laser desorption ionization (MALDI) mass spectrometry: a novel analytical tool in molecular biology and biotechnology. J Biotech, 41:155, 1995.

    Article  CAS  Google Scholar 

  21. Kuwata H, Yip TT, Yip CL, Tomita M, Hutchens TW: Bactericidal domain of lactoferrin: Detection, quantitation and characterization of lactoferricin in serum by SELDI affinity mass spectrometry. Biochem Biophy Res Commun, 245:764, 1998.

    Article  CAS  Google Scholar 

  22. Machold J, Utkin Y, Kirach D, Kaufmann R, Tsetlin V: Photolabeling reveals the proximity of the a-neurotoxin binding site to the M2 helix of the ion channel in the nicotinic acetylcholine receptor. Proc Natl Acad Sci USA, 92:7282, 1995.

    Article  PubMed  CAS  Google Scholar 

  23. Mann M, Shen S, Fenn JB: Electrospray mass spectrometry. In: Gross ML, editor. Mass Spectrometry in the Biological Sciences. New York: Kluwer Academic Publishers; pp. 145–160, 1992.

    Chapter  Google Scholar 

  24. Mann M, Wilm M: Error-tolerant identification of peptides in sequence databases by peptide sequence tags. Anal Chem, 66:4390, 1994.

    Article  PubMed  CAS  Google Scholar 

  25. Mann M, Talbo G: Developments in matrix-assisted laser desorption ionization peptide mass spectrometry. Curr Opin Biotechnol, 7(1): 11, 1996.

    Article  PubMed  CAS  Google Scholar 

  26. Meng CK, Mann M, Fenn JB: Of protons or proteins. Zeitschr F Physik, 10:361, 1988.

    CAS  Google Scholar 

  27. Moore WT: Laser Desorption Mass Spectrometry. In: Fields GB, editor. Methods in Enzymology. New York: Academic Press; 289:520–542, 1997.

    Google Scholar 

  28. Nelson RW, McLean MA, Hutchens TW: Quantitative determination of proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Chem, 66:1408, 1994.

    Article  CAS  Google Scholar 

  29. O’Farrel PH: High-resolution two-dimensional gel electrophoresis of proteins. J Biol Chem, 250:4007, 1975.

    Google Scholar 

  30. Osterling JE: Prostate Specific Antigen: A critical assessment of the most useful tumor marker for adenocarcinoma of the prostate. J Urol, 145:907, 1991.

    Google Scholar 

  31. Patterson SD: From electrophoretically separated proteins to identification: Strategies for sequence and mass analysis. Anal Biochem, 221:1, 1994.

    Article  PubMed  CAS  Google Scholar 

  32. Patterson SD: Matrix-assisted laser desorption/ionization mass spectrometric approaches for the identification of gel-separated proteins in the 5–50pmol range. Electrophoresis, 16:1104, 1995.

    Article  PubMed  CAS  Google Scholar 

  33. Patterson SD: Protein Identification and Characterization by Mass Spectrometry. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, editors. Current Protocols in Molecular Biology. New York: John Wiley & Sons Inc.; unit 10.22, pp. 10.22.1–10.22.24, 1998.

    Google Scholar 

  34. Paweletz CP, Ornstein DK, Gillespie JW, Hutchens TW, Cole KA, Simone N, et al: A novel proteomic approach to monitor carcinogenic disease progression using surface-enhanced laser desorption ionization spectroscopy (SELDI) of laser capture microdissection (LCM)-derived cells from cancer. Proc Amer Assoc Cancer Res, 40:411 (abs. 2717), 1999.

    Google Scholar 

  35. Rasmussen HH, Orntoft TF, Wolf H, Celis JE: Towards a comprehensive database of proteins from the urine of patients with bladder cancer. J Urol, 155:2113, 1996.

    Article  PubMed  CAS  Google Scholar 

  36. Rossi D, Hoffman KL, Janiczek-Dolphin N, Bockbrader H, Parker TD: Tandem-in-Time Mass Spectrometry as a Quantitative Bioanalytical Tool. Anal Chem, 69:4519, 1997.

    Article  PubMed  CAS  Google Scholar 

  37. Siuzdak G: The emergence of mass spectrometry on biochemical research. Proc Natl Acad Sci USA, 91:11290, 1994.

    Article  PubMed  CAS  Google Scholar 

  38. Thiede B, Wittmann-Liebold B, Biernert M, Krause E: MALDI-MS for C-terminal sequence determination of peptides and proteins degraded by carboxypeptidase Y and P. FEBS Lett, 357: 65, 1995.

    Article  PubMed  CAS  Google Scholar 

  39. Vlahou A, Mendrinos S, Kondylis FI, Schellhammer PF, Lynch Jr, DF, Wright Jr GL: Desorption, Ionization Time of Flight Mass Spectrometry (SELDI-TOF-MS): A novel proteomic approach to identify bladder cancer biomarkers. Proceedings of the AACR-NCI-EORTC International Conference. Clin Cancer Res, 5:38675s (abs 688), 1999.

    Google Scholar 

  40. Vorm O, Roepstorff P: Peptide sequence information derived by partial acid hydrolysis and matrix-assisted laser desorption/ionization mass spectrometry. Biol Mass Spectrom, 23:734, 1994.

    Article  PubMed  CAS  Google Scholar 

  41. Wang MC, Valenzuela LA, Murphy GP, Chu TM: Purification of human prostate specific antigen. Invest Urol, 17:159, 1979.

    PubMed  CAS  Google Scholar 

  42. Whittal RM, Keller BO, Liang L: Nanoliter chemistry combined with mass spectrometry for peptide mapping of proteins from single mammalian cell lysates. Anal Chem, 70:5344, 1998.

    Article  PubMed  CAS  Google Scholar 

  43. Wilking MR, Sanchez J-C, Gooley AA, Appel RD, Humphrey-Smith I, Hochstrasser DF, et al: Progress with proteome projects: Why all proteins expressed by a genome should be identified and how to do it. Biotechnol Genet Eng Rev, 13:19, 1995.

    Google Scholar 

  44. Wilm M, Shevchenko A, Houthaeve T, Breit S, Schweigerer L, Fotsis T, et al: Femtomole sequencing of proteins from acrylamide gels by nano-electrospray mass spectrometry. Nature, 379:466, 1996.

    Article  PubMed  CAS  Google Scholar 

  45. Wright Jr. GL, Haley C, Beckett M-L, Schellhammer PF: Expression of prostate specific membrane antigen in normal, benign and malignant prostate tissues. Urol Oncol, 1:18, 1995.

    Article  PubMed  Google Scholar 

  46. Wright Jr. GL, Cazares LH, Leung S-M, Nasim S, Adam B-L, Yip T-T, et al: ProteinChipâ„¢ surface enhanced laser desorption/ionization (SELDI) mass spectrometry: a novel protein biochip technology for detection of prostate cancer biomarkers in complex protein mixtures. Prostate cancer and prostatic diseases, in press.

    Google Scholar 

  47. Yip TT, Van de Water J, Greshwin ME, Coppel R., Hutchens TW: Cryptic antigenic determinants on the extracellular pyruvate dehydrogenase complex/mimeotope found in primary biliary cirrhosis. J Biol Chem, 271:32825, 1996.

    Article  PubMed  CAS  Google Scholar 

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Vlahou, A., Schellhammer, P.F., Wright, G.L. (2003). Application of a Novel Protein Chip Mass Spectrometry Technology for the Identification of Bladder Cancer-Associated Biomarkers. In: Atala, A., Slade, D. (eds) Bladder Disease, Part A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8889-8_4

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  • DOI: https://doi.org/10.1007/978-1-4419-8889-8_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4707-1

  • Online ISBN: 978-1-4419-8889-8

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