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Approaches to Devise Antibody Purification Processes by Chromatography

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Antibodies

Abstract

Monoclonal antibodies and more largely immunoglobulins along with all their fragments and engineered forms represent today the largest class of produced and purified protein in number and quantity. New potential applications of antibodies in their native form or various engineered constructs actually continue to stimulate therapeutic areas. Expected high dosage levels imply that their purity has to meet stringent requirements. It means also that the production cost per dose compared to other therapeutic biomolecules has to be kept low. To achieve these goals it is anticipated that effective, low cost productions and purification strategies will be put in place.

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Authors and Affiliations

  1. Ciphergen Biosystems — Biosepra, 48, Avenue des Genottes, Cergy, France

    Egisto Boschetti

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  1. Egisto Boschetti
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  1. Littlebourne, Kent, UK

    G. Subramanian

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Boschetti, E. (2004). Approaches to Devise Antibody Purification Processes by Chromatography. In: Subramanian, G. (eds) Antibodies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8877-5_4

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  • DOI: https://doi.org/10.1007/978-1-4419-8877-5_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4702-6

  • Online ISBN: 978-1-4419-8877-5

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