Advertisement

Transgenic Technology for Monoclonal Antibody Production

An overview of transgenic animal and plant systems
Chapter
  • 275 Downloads

Abstract

Monoclonal antibodies account for between one-third and one-half of all pharmaceutical products in development and in human clinical trials. Both the nature of monoclonal antibody therapies, and the relatively large size of the monoclonal antibody molecules dictate that the production requirements for many of these therapeutic monoclonal antibody products will be 100 kilograms or more per year. It is widely acknowledged that there is currently a worldwide shortage of biomanufacturing capacity, and that the gap between biomanufacturing capacity and the active pharmaceutical ingredient material requirements for these products is expected to increase.

Keywords

Recombinant Protein Expression Cassette Nuclear Transfer Unit Production Cost Surrogate Mother 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Biotechnology Industry Organization website: www.bio.orgGoogle Scholar
  2. Li-Chan, E., Powrie, W., and Nakai, S., 1995, The Chemistry of Eggs and Egg Products. In Egg Science and Technology, Fourth Edition (Stadelman, W., and Cotterill, O., eds.), Haworth Press, New York, pp. 105–175.Google Scholar
  3. Stadelman, W., 1995, Egg-Production Practices. In Egg Science and Technology, Fourth Edition (Stadelman, W., and Cotterill, O., eds.), Haworth Press, New York, pp. 9–37.Google Scholar
  4. Sugino, H., Nitoda, T., and Juneja, L., 1997, General Chemical Composition of Hen Eggs. In Hen Eggs: Their Basic and Applied Science (Yamamoto, T., Juneja, L., Hatta, H., and Kim, M., eds.), CRC Press, Florida, pp. 13–24.Google Scholar

Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  1. 1.GeneWorks, Inc.Ann ArborUSA

Personalised recommendations