Skip to main content

Nuclear poly(ADPR)Polymerase expression and activity in rat astrocytes culture: effects of bFGF

  • Conference paper
ADP-Ribosylation Reactions

Abstract

Due to the availability of rat poly(ADPR)P cDNA (Thibodeau et al.,1989), the investigation of the poly(ADPR)P gene expression, in various experimental conditions, became possible. Long term primary cultures of rat astrocytes were used to investigate the poly(ADPR)P gene expression during the proliferation and the differentiation. In addition, the effects of basic Fibroblast Growth Factor (bFGF) have been investigated.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Berger, N. A., G. Weber, A. S. Kaichi, and S. J. Petzold. 1978. Relation of poly(Adenosine diphosphoribose) synthesis to DNA synthesis and cell growth. B.B.A. 519:105–117.

    CAS  Google Scholar 

  • Cesarone, C. F., L. Scarabelli, A. I. Scovassi, R. Izzo, M. Menegazzi, A. Carcereri De Prati, M. Orunesu, and U. Bertazzoni. 1990. Changes in activity and mRNA levels of Poly(ADP-ribose)polymerase during rat liver regeneration. B.B.A. 1087:241–246.

    CAS  Google Scholar 

  • Farzaneh, F., and C. K. Pearson. 1979. The activity and properties of poly(Adenosine diphosphate ribose) polymerase in vitro during the embryonic development of South African clawed toad Xenopus laevis. Dev. Biol. 72:254–265.

    Article  PubMed  CAS  Google Scholar 

  • Ittel, M.E., J. Jongstra-Bilen, C. Rochette-Egly, and P. Mandel. 1983. Involvement of poly ADP-ribose polymerase in the initiation of phytohemagglutinin induced human lymphocyte proliferation. B.B.R.C. 116:428–434.

    CAS  Google Scholar 

  • Ohashi, Y., K. Ueda, O. Hayaishi, K. Ikai, and O. Niwa. 1984. Induction of murine teratocarcinoma cell differentiation by suppression of poly(ADP-­ribose) synthesis. Proc. Natl. Acad. Sci. USA, 81:7132–7136.

    Article  PubMed  CAS  Google Scholar 

  • Tanigushi, T., K. Yamauchi, T. Yamamoto, K. Toyoshima, N. Harada, H. Tanaka, S. Takahashi, H. Yamamoto, and S. Fujimoto. 1988a. Depression in gene expression for poly(ADP-ribose) synthetase during the interferon-γ-induced activation process of murine macrophage tumor cells. Eur. J. Biochem. 171:571–575.

    Article  Google Scholar 

  • Tanigushi, T., K. Morisawa, M. Ogawa, H. Yamamoto, and S. Fujimoto. 1988b. Decrease in the level of poly(ADP-ribose) synthetase during Nerve Growth Factor-promoted neunte outgrowth in rat pheochromocytoma PC12 cells.B.B.R.C. 154:1034–1040.

    Google Scholar 

  • Thibodeau, J., G. Gradwhol, C. Dumas, S. Clairoux-Moreau, G. Burnet, C. Penning, G. Poirier, and P. Moreau. 1989. Cloning rodent cDNA encoding the poly(ADP-ribose)polymerase catalytic domain and analysis of mRNA levels during the cell cycle. Biochem. Cell Biol. 67:653–660.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer Science+Business Media New York

About this paper

Cite this paper

Chabert, M.G., Niedergang, C.P., Hog, F., Partisani, M., Mandel, P. (1992). Nuclear poly(ADPR)Polymerase expression and activity in rat astrocytes culture: effects of bFGF. In: Poirier, G.G., Moreau, P. (eds) ADP-Ribosylation Reactions. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8718-1_8

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-8718-1_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-6456-9

  • Online ISBN: 978-1-4419-8718-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics