Poly(ADP—Ribose)Polymerase in Xenopus laevis
Among the different biological systems in which poly(ADP-ribosyl)ation has been studied, cell lines have been widely used, especialy to investigate the role of poly(ADP-ribose)polymerase (PARP) in DNA repair(1). Other systems such as regenerating rat liver (2) or mitogen stimulated lymphocytes (3) permitted several authors to suggest the implication of the PARP in DNA replication and cell proliferation. Even so, one has to admit that the precise biological function of poly(ADP-ribosyl)ation of proteins acceptors is still unclear.
KeywordsZinc EDTA Electrophoresis Germinal Progesterone
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