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State-Dependent Plasticity of Neural Responses to 70dB Clicks Along Central, Primary, Auditory Transmission Pathways

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Acoustical Signal Processing in the Central Auditory System

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Abstract

The coding and transmission of acoustic messages is affected profoundly by state-dependent plasticity along central neural transmission pathways. Early studies of spike activity (Engel and Woody, 1972; Olds et al, 1972; Oleson et al 1975; Woody et al, 1976) found evidence of widespread changes in transmissions within the auditory system after conditioning with an acoustic CS. Many forms of conditioning have been shown to produce changes in activity (McCormick and Thompson, 1984; Miller et al, 1982; Recanzone et al, 1993; Scheich et al 1993; Weinberger et al, 1993). Studies of single unit activity have now established that responses to click in the cochlear nucleus, the first central relay of the auditory system, increase in magnitude after eyeblink conditioning with click as a CS, and further changes in activity have been found in the ventral portion of the nucleus after sensitization (Woody et al 1992, 1994). These state-dependent changes in activity will affect transmission at higher levels because all acoustic transmissions must obligatorily pass through the cochlear nucleus.

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Authors and Affiliations

  1. Mental Retardation Research Center Brain Research Institute, UCLA Medical Center, Los Angeles, California, 90024

    Charles D. Woody

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  1. Charles D. Woody
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  1. Academy of Sciences of the Czech Republic, Prague, Czech Republic

    Josef Syka

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Woody, C.D. (1997). State-Dependent Plasticity of Neural Responses to 70dB Clicks Along Central, Primary, Auditory Transmission Pathways. In: Syka, J. (eds) Acoustical Signal Processing in the Central Auditory System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8712-9_46

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  • DOI: https://doi.org/10.1007/978-1-4419-8712-9_46

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4673-9

  • Online ISBN: 978-1-4419-8712-9

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