Abstract
The proto-oncogene c-fos is a member of a large class of “immediate early gene” which is rapidly and transiently expressed in neurons in response to a wide variety of ex- ternal stimuli (Morgan and Curran, 1991). Fos, the protein product of the gene c-fos, acts as a transcription regulator for the expression of other target genes (Morgan and Curran, 1991). In the absence of inputs or strong activations, there is a low basal Fos spontaneous activity (Morgan and Curran, 1991). Thereby, the increase of the c-fos expression can be used as a marker of neuronal activity (Hunt et al., 1987; Sagar et al., 1988; Dragunov and Faull, 1989).
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Herve-Minvielle, A., Carretta, D., Bajo, V.M., Villa, A.E.P., Rouiller, E.M. (1997). Evolution of C-Fos Expression in Auditory Structures During a Sensori-Motor Learning in Rats. In: Syka, J. (eds) Acoustical Signal Processing in the Central Auditory System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8712-9_4
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