Structural Basis for Signal Processing
The synaptic nest represents a structural pattern and a concept whose time have come for serious consideration in the effort to understand the mechanisms responsible for signal coding in the auditory system. Synaptic nests have an organization which makes it difficult to explain mechanisms of signal processing based on current assumptions about the primacy of cell types and their discrete circuits. Synaptic nests occur in many other parts of the central nervous system, including other sensory nuclei and the cerebellum, although this is not very well appreciated at present. Thus their functional significance has general implications for understanding the function of the nervous system.
KeywordsMossy Fiber Cochlear Nucleus Principal Cell Mitt Cell Dorsal Cochlear Nucleus
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- Altaian J, Bayer SA (1977) Time of origin and distribution of a new cell type in the rat cerebellar cortex. Exp Brain Res 29: 265–274.Google Scholar
- Bilak SR, Morest DK (1996) Differential expression of the metabotropic glutamate receptor mGluRl in the mouse cochlear nucleus: an in situ/immunohistochemistry study of specific neuron types. (Submitted)Google Scholar
- Hutson KA, Morest DK (1994) Ultrastructure of small cell regions in the cochlear nucleus (CN) of chinchilla. Assoc. Res. Otolaryngol. Abstr. 17: 27.Google Scholar
- Kidd M (1962) Electron microscopy of the inner plexiform layer of the retina in the cat and the pigeon. J Anat (Lond) 96: 179–187.Google Scholar
- Kolston J, Osen KK, Hackney CM, Ottersen CP, and Storm-Mathisen J (1992) An atlas of glycine-and GABA-like immunoreactivity and colocalization in the cochlear nuclear complex of the guinea pig. Anat Einbryol 186:443–65.Google Scholar
- LeDoux JE, Sakaguchi A, Reis DJ (1984) Subcortical efferent projections of the medial geniculate nucleus mediate emotional responses conditioned to acoustic stimuli. J Neuroscience 4: 683–698.Google Scholar
- Morel A (1980) Codage des sons dans le corps genouillé médian du chat: évaluation de l’organisation tonotopique de ses différents noyaux. Doctoral dissertation. Université de Lausanne. Zurich: Juris Druck + Verlag.Google Scholar
- Morest DK (1970) Electron microscopic study of the synaptic organization in the medial geniculate body of the cat. Anat Rec 166: 351.Google Scholar
- Morest DK (1993) the cellular basis for signal processing the mammalian cochlear nuclei. In MD Merchan, JM Juiz, DA Godfrey and E Mugnaini (eds). The Mammalian Cochlear Nuclei: Organization and Function. N.Y.: Plenum Press, pp 195–210.Google Scholar
- Oliver DL, Potashner SJ, Jones DR and Morest DK (1983) Selective labeling of spiral ganglion and granule cells with D-aspartate in the auditory system of cat and guinea pig. J Neuroscience 3: 455–472.Google Scholar
- Peters A, Palay SL (1966) The morphology of laminae A and Al of the dorsal nucleus of the lateral geniculate body of the cat. J Anat (Lond) 100: 451–486.Google Scholar