Abstract
In rats, recent thymic migrants (RTM) are phenotypically characterized by the presence of Thy-1 and the lack of RT6 and CD45RC expression. Upon peripheral maturation these cells develop into Thy-1- T cells that express both RT6 and CD45RC (1-3). For the bulk of RTM this transition was shown to occur through at least two subsequent intermediate stages in which T cells first express the Thy-1+/RT67CD45RC~ and later the Thy-1+RT6+CD45RC+ phenotype (1,4).
This study was supported by the Dutch Diabetes Foundation
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Groen, H., Pater, J.M., Klatter, F.A., Nieuwenhuis, P., Rozing, J. (1997). Expression of RT6, but Not CD45RC, is Disturbed on Immature Peripheral T Cells In the BB Rat. In: Haag, F., Koch-Nolte, F. (eds) ADP-Ribosylation in Animal Tissues. Advances in Experimental Medicine and Biology, vol 419. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8632-0_32
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DOI: https://doi.org/10.1007/978-1-4419-8632-0_32
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