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Biomaterials Pathology

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Abdominal Wall Hernias

Abstract

The modern era of biomaterials was born with the discovery of antibiotics in the mid-twentieth century. Antibiotics enabled surgeons to control the bacteria that invariably settled on a medical device from the operating room atmosphere immediately before implantation. Once bacteria were under control, differences among various materials and the biological responses they provoked became apparent, and the need to develop materials that exhibited improved “biocompatibility” emerged. In this chapter, we present a brief but comprehensive review of the essential factors contributing to biomaterials and their induced biological response, which we term bioreactivity.

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Authors and Affiliations

  1. Department of Surgery, University of California at Los Angeles, School of Medicine, Los Angeles, CA 90095, USA

    Nir Kossovsky MD

  2. Department of Pathology, Mount Sinai Hospital, Toronto, Ontario, M5G 1X4, Canada

    Charles J. Freiman MD & David Howarth MD

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  1. Nir Kossovsky MD
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  2. Charles J. Freiman MD
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  3. David Howarth MD
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Editors and Affiliations

  1. Toronto, Canada

    Robert Bendavid MD

  2. Haifa, Israel

    Jack Abrahamson MD

  3. Indianapolis, IN, USA

    Maurice E. Arregui MD

  4. Reims, France

    Jean Bernard Flament MD

  5. Los Angeles, CA, USA

    Edward H. Phillips MD

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Kossovsky, N., Freiman, C.J., Howarth, D. (2001). Biomaterials Pathology. In: Bendavid, R., Abrahamson, J., Arregui, M.E., Flament, J.B., Phillips, E.H. (eds) Abdominal Wall Hernias. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8574-3_28

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  • DOI: https://doi.org/10.1007/978-1-4419-8574-3_28

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