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Idiopathic Hypersomnia

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Narcolepsy

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Abstract

Idiopathic hypersomnia (IHS) is a rare and poorly defined sleep disorder characterized by excessive daytime sleepiness (EDS) despite undisturbed nocturnal sleep. Historically, the concept of IHS was developed in the 1950s to separate patients with unexplained daytime sleepiness from those with classical narcolepsy. Two forms of IHS were distinguished solely on clinical grounds based on (1) typical features of EDS and sleep (continuous EDS, nonirresistible naps, difficulties upon awakening including sleep drunkenness, prolonged, and nonrefreshing naps), (2) a familial pattern, and (3) a poor response to treatment. Later, documentation of objective sleepiness together with the absence of more than two sleep onset REMs (SOREMs) in the multiple sleep latency test (MSLT) became important supportive criteria.

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Authors and Affiliations

  1. Center of Sleep Medicine, Klinik Barmelweid AG, CH, 5017, Barmelweid, Switzerland

    Ramin Khatami

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  1. Ramin Khatami
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Correspondence to Ramin Khatami .

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Editors and Affiliations

  1. , Department of Neurology, University Hospital of Zurich, Frauenklinikstrasse 26, Zurich, 8091, Switzerland

    Christian R. Baumann

  2. Neurocenter EOC of Southern Switzerland, Department of Neurology, University Hospital Zurich, Via Tesserete 46, Lugano, 6903, Switzerland

    Claudio L. Bassetti

  3. and Harvard Medical School, Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, 02215, Massachusetts, USA

    Thomas E. Scammell

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Khatami, R. (2011). Idiopathic Hypersomnia. In: Baumann, C., Bassetti, C., Scammell, T. (eds) Narcolepsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8390-9_33

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  • DOI: https://doi.org/10.1007/978-1-4419-8390-9_33

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