Skip to main content
SpringerLink
Log in

Parasomnias in Narcolepsy with Cataplexy

  • Chapter
  • First Online:
Narcolepsy

Abstract

Narcolepsy with cataplexy is a disabling disorder characterized by excessive daytime sleepiness (EDS) and abnormal rapid eye movement (REM) sleep manifestations including cataplexy (sudden loss of muscle tone triggered by strong emotions), sleep paralysis, hypnagogic hallucinations, and sleep-onset REM periods [1].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Dauvilliers Y, Arnulf I, Mignot E. Narcolepsy with cataplexy. Lancet. 2007;369:499–511.

    Article  PubMed  Google Scholar 

  2. American Academy of Sleep Medicine. International Classification of Sleep Disorders. 2nd ed: Diagnostic and coding manual. Westchester, IL: American Academy of Sleep Medicine; 2005.

    Google Scholar 

  3. Dauvilliers Y, Billiard M, Montplaisir J. Clinical aspects and pathophysiology of narcolepsy. Clin Neurophysiol. 2003;114:2000–17.

    Article  PubMed  Google Scholar 

  4. Ferri R, Miano S, Bruni O, et al. NREM sleep alterations in narcolepsy/cataplexy. Clin Neurophysiol. 2005;116:2675–84.

    Article  PubMed  Google Scholar 

  5. Plazzi G, Serra L, Ferri R. Nocturnal aspects of narcolepsy with cataplexy. Sleep Med Rev. 2008;12:109–28.

    Article  PubMed  Google Scholar 

  6. Mayer G, Meier-Ewert K. Motor dyscontrol in sleep of narcoleptic patients (a lifelong development?). J Sleep Res. 1993;2:143–8.

    Article  PubMed  Google Scholar 

  7. Schenck CH, Bundlie SR, Ettinger MG, Mahowald MW. Chronic behavioral disorders of human REM sleep: a new cathegory of parasomnia. Sleep. 1986;9:293–308.

    PubMed  CAS  Google Scholar 

  8. Fantini ML, Corona A, Clerici S, Ferini-Strambi L. Aggressive dream content without daytime aggressiveness in REM sleep behavior disorder. Neurology. 2005;11(65):1010–5.

    Article  Google Scholar 

  9. Lapierre O, Montplasir J. Polysomnographic features of REM sleep behavior disorder: development of a scoring method. Neurology. 1992;42:1371–4.

    Article  PubMed  CAS  Google Scholar 

  10. Dauvilliers Y, Rompré S, Gagnon JF, Vendette M, Petit D, Montplaisir J. REM sleep characteristics in narcolepsy and REM sleep behavior disorder. Sleep. 2007;30:844–9.

    PubMed  Google Scholar 

  11. Ohayon MM, Caulet M, Priest RG. Violent behavior during sleep. J Clin Psychiatry. 1997;58:369–76.

    Article  PubMed  CAS  Google Scholar 

  12. de Barros-Ferreira M, Lairy GC. Ambiguous sleep in narcolepsy. In: Guilleminault C, Dement WC, Passouant P, editors. Narcolepsy. Proceedings of the first International Symposium on Narcolepsy, July 1975, Montpellier, France, New York: Spectrum publications; 1976. p. 57–75.

    Google Scholar 

  13. Nightingale S, Orgill JC, Ebrahim IO, de Lacy SF, Agrawal S, Williams AJ. The association between narcolepsy and REM behavior disorder (RBD). Sleep Med. 2005;6:253–8.

    Article  PubMed  CAS  Google Scholar 

  14. Mattarozzi K, Bellucci C, Campi C, et al. Clinical, behavioural and polysomnographic correlates of cataplexy in patients with narcolepsy/cataplexy. Sleep Med. 2008;9:425–33.

    Article  PubMed  Google Scholar 

  15. Schenck CH, Mahowald MW. Motor dyscontrol in narcolepsy: rapid-eye-movement (REM) sleep without atonia and REM sleep behavior disorder. Ann Neurol. 1992;32:3–10.

    Article  PubMed  CAS  Google Scholar 

  16. Nevsimalova S, Prihodova I, Kemlink D, Lin L, Mignot E. REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy. Sleep Med. 2007;8:784–6.

    Article  PubMed  Google Scholar 

  17. Geisler P, Meier-Ewert K, Matsubayshi K. Rapid eye movements, muscle twitches and sawtooth waves in the sleep of narcoleptic patients and controls. Electro-encephalogr Clin Neurophysiol. 1987;67:499–507.

    Article  PubMed  CAS  Google Scholar 

  18. Hishikawa Y, Wakamatsu H, Furuya E, et al. Sleep satiation in narcoleptic patients. Electroencephalogr Clin Neurophysiol. 1976;41:1–18.

    Article  PubMed  CAS  Google Scholar 

  19. Ferri R, Franceschini C, Zucconi M, et al. Searching for a marker of REM sleep behavior disorder: submentalis muscle EMG amplitude analysis during sleep in patients with narcolepsy/cataplexy. Sleep. 2008;31:1409–17.

    PubMed  Google Scholar 

  20. Ferri R, Manconi M, Plazzi G, et al. A quantitative statistical analysis of the submentalis muscle EMG amplitude during sleep in normal controls and patients with REM sleep behavior disorder. J Sleep Res. 2008;17:89–100.

    Article  PubMed  Google Scholar 

  21. Plazzi G, Corsini R, Provini F, et al. REM sleep behavior disorders in multiple system atrophy. Neurology. 1997;48:1094–7.

    Article  PubMed  CAS  Google Scholar 

  22. Schuld A, Kraus T, Haack M, Hinze-Selch D, Pollmächer T. Obstructive sleep apnea syndrome induced by clonazepam in a narcoleptic patient with REM-sleep-behavior disorder. J Sleep Res. 1999;8:321–2.

    Article  PubMed  CAS  Google Scholar 

  23. Yeh SB, Schenck CH. A case of marital discord and secondary depression with attempted suicide resulting from REM sleep behavior disorder in a 35-year-old woman. Sleep Med. 2004;5:151–4.

    Article  PubMed  Google Scholar 

  24. Schenck CH, Mahowald MW. Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults. Am J Med. 1996;100:333–7.

    Article  PubMed  CAS  Google Scholar 

  25. Boeve BF, Silber MH, Ferman TJ. Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients. Sleep Med. 2003;4:281–4.

    Article  PubMed  Google Scholar 

  26. Billiard M, Bassetti C, Dauvilliers Y, Dolenc-Groselj L, Lammers GJ, Mayer G, et al. EFNS Task Force EFNS guidelines on management of narcolepsy. Eur J Neurol. 2006;13:1035–48.

    Article  PubMed  CAS  Google Scholar 

  27. Hishikawa Y, Shimizu T. Physiology of REM sleep, cataplexy, and sleep paralysis. Adv Neurol. 1995;67:245–71.

    PubMed  CAS  Google Scholar 

  28. Girard T, Cheyne A. Timing of spontaneous sleep-paralysis episodes. J Sleep Res. 2006;15:222–9.

    Article  PubMed  Google Scholar 

  29. Ohayon MM, Zulley J, Guilleminault C, Smirne S. Prevalence and pathologic associations of sleep paralysis in the general population. Neurology. 1999;52:1194–2000.

    Article  PubMed  CAS  Google Scholar 

  30. Szklo-Coxe M, Young T, Finn L, Mignot E. Depression: relationships to sleep paralysis and other sleep disturbances in a community sample. J Sleep Res. 2007;16:297–312.

    Article  PubMed  Google Scholar 

  31. Dauvilliers Y, Paquereau J, Bastuji H, Drouot X, Weil JS, Viot-Blanc V. Psychological health in central hypersomnias: the French Harmony study. J Neurol Neurosurg Psychiatry. 2009;80:636–41.

    Article  PubMed  CAS  Google Scholar 

  32. Fortuyn HA, Lappenschaar GA, Nienhuis FJ, et al. Psychotic symptoms in narcolepsy: phenomenology and a comparison with schizophrenia. Gen Hosp Psychiatry. 2009;31:146–54.

    Article  PubMed  Google Scholar 

  33. Ohayon MM. Prevalence of hallucinations and their pathological associations in the general population. Psychiatry Res. 2000;97:153–64.

    Article  PubMed  CAS  Google Scholar 

  34. Ribstein M. Hypnagogic hallucinations. In: Guilleminault C, Dement WC, Passouant P, editors. Narcolepsy. Proceedings of the first international symposium on narcolepsy, July 1975. Montpellier, France, New York: Spectrum Publications; 1976. p. 145–60.

    Google Scholar 

  35. Laberge L, Tremblay RE, Vitaro F, Montplaisir J. Development of parasomnias from childhood to early adolescence. Pediatrics. 2000;106:67–74.

    Article  PubMed  CAS  Google Scholar 

  36. Pilon M, Zadra A, Joncas S, Montplaisir J. Hypersynchronous delta waves and somnambulism: brain topography and effect of sleep deprivation. Sleep. 2006;29:77–84.

    PubMed  Google Scholar 

  37. Zadra A, Pilon M, Montplaisir J. Polysomnographic diagnosis of sleepwalking: effects of sleep deprivation. Ann Neurol. 2008;63:513–9.

    Article  PubMed  Google Scholar 

  38. Dauvilliers Y, Maret S, Tafti M. Genetics of normal and pathological sleep in humans. Sleep Med Rev. 2005;9:91–100.

    Article  PubMed  CAS  Google Scholar 

  39. Lecendreux M, Bassetti C, Dauvilliers Y, Mayer G, Neidhart E, Tafti M. HLA and genetic susceptibility to sleepwalking. Mol Psychiatry. 2003;8:114–7.

    Article  PubMed  CAS  Google Scholar 

  40. Reynolds III CF, Christiansen CL, Taska LS, et al. Sleep in narcolepsy and depression. Does it all look alike? J Nerv Ment Dis. 1983;171:290–5.

    Article  PubMed  Google Scholar 

  41. Schenck CH, Boyd JL, Mahowald MW. A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases. Sleep. 1997;20:972–81.

    PubMed  CAS  Google Scholar 

  42. Mayer G, Lattermann A, Mueller-Eckhardt G, Svanborg E, Meier-Ewert K. Segregation of HLA genes in multicase narcolepsy families. J Sleep Res. 1998;7:127–33.

    Article  PubMed  CAS  Google Scholar 

  43. Chabas D, Foulon C, Gonzalez J, Nasr M, Lyon-Caen O, Willer JC, et al. Eating disorder and metabolism in narcoleptic patients. Sleep. 2007;30:1267–73.

    PubMed  Google Scholar 

  44. Fortuyn HA, Swinkels S, Buitelaar J, et al. High prevalence of eating disorders in narcolepsy with cataplexy: a case-control study. Sleep. 2008;31:335–41.

    PubMed  Google Scholar 

  45. Kotagal S, Krahn LE, Slocumb N. A putative link between childhood narcolepsy and obesity. Sleep Med. 2004;5:147–50.

    Article  PubMed  Google Scholar 

  46. Lammers GJ, Pijl H, Iestra J, Langius JA, Buunk G, Meinders AE. Spontaneous food choice in narcolepsy. Sleep. 1996;19:75–6.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre de Référence Nationale Maladie Rare – Narcolepsie et Hypersomnie Idiopathique, Service de Neurologie, Hôpital Gui-de-Chauliac, Inserm U1061, Montpellier, France

    Yves Dauvilliers

Authors
  1. Yves Dauvilliers
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Régis Lopez
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yves Dauvilliers .

Editor information

Editors and Affiliations

  1. , Department of Neurology, University Hospital of Zurich, Frauenklinikstrasse 26, Zurich, 8091, Switzerland

    Christian R. Baumann

  2. Neurocenter EOC of Southern Switzerland, Department of Neurology, University Hospital Zurich, Via Tesserete 46, Lugano, 6903, Switzerland

    Claudio L. Bassetti

  3. and Harvard Medical School, Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, 02215, Massachusetts, USA

    Thomas E. Scammell

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Dauvilliers, Y., Lopez, R. (2011). Parasomnias in Narcolepsy with Cataplexy. In: Baumann, C., Bassetti, C., Scammell, T. (eds) Narcolepsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8390-9_27

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-8390-9_27

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-8389-3

  • Online ISBN: 978-1-4419-8390-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation