Skip to main content

Behavioural, Biopsychosocial, and Cognitive Models of Autism Spectrum Disorders

  • Chapter
  • First Online:
International Handbook of Autism and Pervasive Developmental Disorders

Part of the book series: Autism and Child Psychopathology Series ((ACPS))

Abstract

Autism spectrum disorder (ASD) comprises a range of developmental disorders including autistic disorder, Asperger’s disorder, and pervasive developmental disorder not otherwise specified/atypical autism, each of which is characterized by a triad of impairments in social interaction, communication, and restricted, repetitive behaviours and interests (RRBIs) (American Psychiatric Association, 2000; World Health Organization, 1993). ASD was originally identified and described in 1943 by Kanner, who believed the disorder to be biologically based. However, in the following decades, psychosocial explanations for ASD began to gain influence. Most notably, Bettelheim (1967) attributed the development of ASD as a response to emotionally “cold” parenting. Although this theory was influential for a significant period of time, it has not received empirical support, and it is now widely agreed that ASD is a biologically based disorder. Twin studies have consistently indicated that ASD is a highly heritable disorder (e.g. Bailey et al., 1995; Folstein & Rutter, 1977; Steffenburg, Hellgren, Gillberg, Jakobsen, & Bohman, 1989). Furthermore, although molecular genetic studies have not yet established a set of necessary and sufficient genes that cause the disorder, they have begun to identify a set of genes that are reliably associated with ASD (International Molecular Genetic Study of Autism Consortium, 1998, 2001, 2005).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 429.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 549.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 799.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Ambery, F. Z., Russell, A. J., Perry, K., Morris, R., & Murphy, D. G. (2006). Neuropsychological functioning in adults with Asperger syndrome. Autism, 10, 551–564.

    PubMed  Google Scholar 

  • American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text revision). New York: American Psychiatric Association.

    Google Scholar 

  • Austin, E. J. (2005). Personality correlates of the broader autism phenotype as assessed by the Autism Spectrum Quotient (AQ). Personality and Individual Differences, 38, 451–460.

    Google Scholar 

  • Auyeung, B., Baron-Cohen, S., Wheelwright, S., & Allison, C. (2005). The Autism Spectrum Quotient: Children’s version (AQ-Child). Journal of Autism and Developmental Disorders, 38, 1230–1240.

    Google Scholar 

  • Baddeley, A. (2000). The episodic buffer: A new component of working memory? Trends in Cognitive Sciences, 4, 417–423.

    PubMed  Google Scholar 

  • Bailey, A., LeCouteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., et al. (1995). Autism as a strongly genetic disorder: Evidence from a British twin study. Psychological Medicine, 25, 63–77.

    PubMed  Google Scholar 

  • Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985). Does the autistic child have a theory of mind? Cognition, 21, 37–46.

    PubMed  Google Scholar 

  • Baron-Cohen, S., Wheelwright, S. J., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31, 5–17.

    PubMed  Google Scholar 

  • Bennetto, L., Pennington, B. F., & Rogers, S. J. (1996). Intact and impaired memory functions in autism. Child Development, 67, 1816–1835.

    PubMed  Google Scholar 

  • Bettelheim, B. (1967). The empty fortress: Infantile autism and the birth of self. New York: The Free Press.

    Google Scholar 

  • Bishop, D. V. M. (1989). Autism, Asperger’s syndrome and semantic-pragmatic disorder: Where are the boundaries? International Journal of Language and Communication Disorders, 24, 107–121.

    Google Scholar 

  • Bishop, D. V. M. (2006). Developmental cognitive genetics: How psychology can inform genetics and vice versa. Quarterly Journal of Experimental Psychology, 59, 1153–1168.

    Google Scholar 

  • Bishop, D. V. M., Bishop, S. J., Bright, P., James, C.,Delaney, T., & Tallal, P. (1999). Different origin of auditory and phonological processing problems in children with language impairment: Evidence from a twin study. Journal of Speech, Language and Hearing Research, 42, 155–168.

    Google Scholar 

  • Bodfish, J. W., Symons, C. S., & Lewis, M. H. (1999). The Repetitive Behavior Scales (RBS). Western Carolina Center Research Reports.

    Google Scholar 

  • Bölte, S., Holtman, M., Poustka, F., Scheurich, A., & Schmidt, L. (2007). Gestalt perception and local-global processing in high-functioning autism. Journal of Autism and Developmental Disorders, 37, 1493–1507.

    PubMed  Google Scholar 

  • Boucher, J. (2006). Is the search for a unitary explanation of autistic spectrum disorders justified? Journal of Autism and Developmental Disorders, 36, 289.

    PubMed  Google Scholar 

  • Bowler, D. M. (1992). ‘Theory of mind’ in Asperger’s syndrome. Journal of Child Psychology and Psychiatry, 33, 877–893.

    PubMed  Google Scholar 

  • Boyd, B. A., McBee, M., Holtzclaw, T., Baranek, G. T., & Bodfish, J. W. (2009). Relationships among repetitive behaviors, sensory features, and executive functions in high functioning autism. Research in Autism Spectrum Disorders, 3, 959–966.

    PubMed  Google Scholar 

  • Brock, J., Brown, C. C., Boucher, J., & Rippon, G. (2002). The temporal binding deficit hypothesis of autism. Development and Psychopathology, 14, 209–224.

    PubMed  Google Scholar 

  • Cambridge Cognition. (1996). CANTAB®. Cambridge: Cambridge Cognition Limited.

    Google Scholar 

  • Caron, M. J., Mottron, L., Berthiaume, C., & Dawson, M. (2006). Cognitive mechanisms, specificity and neural underpinnings of visuospatial peaks in autism. Brain, 129, 1789–1802.

    PubMed  Google Scholar 

  • Caron, C., & Rutter, M. (1991). Comorbidity in child psychopathology: Concepts, issues and research strategies. Journal of Child Psychology and Psychiatry, 32, 1063–1080.

    PubMed  Google Scholar 

  • Carrington, S. J., & Bailey, A. J. (2009). Are there theory of mind regions in the brain? A review of the neuroimaging literature. Human Brain Mapping, 30, 2313–2335.

    PubMed  Google Scholar 

  • Castelli, F., Frith, C., Happe, F., & Frith, U. (2002). Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain, 125, 1839–1849.

    PubMed  Google Scholar 

  • Christ, S. E., Holt, D. D., White, D. A., & Green, L. (2007). Inhibitory control in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1155–1165.

    PubMed  Google Scholar 

  • Constantino, J. N. (2002). The social responsiveness scale. Los Angeles: Western Psychological Services.

    Google Scholar 

  • Constantino, J. N., Gruber, C. P., Davis, S., Hayes, S., Passanante, N., & Przybeck, T. (2004). The factor structure of autistic traits. Journal of Child Psychology and Psychiatry, 45, 719–726.

    PubMed  Google Scholar 

  • Constantino, J., Przybeck, J., Freisen, D., & Todd, R. D. (2000). Reciprocal social behavior in children with and without pervasive developmental disorders. Journal of Developmental & Behavioral Pediatrics, 21, 2–11.

    Google Scholar 

  • Constantino, J. N., & Todd, R. D. (2003). Autistic traits in the general population: A twin study. Archives of General Psychiatry, 60, 524–530.

    PubMed  Google Scholar 

  • Damasio, A. R., & Maurer, R. G. (1978). Neurological model for childhood autism. Archives of Neurology, 35, 777–786.

    PubMed  Google Scholar 

  • David, N., Gawronski, A., Santos, N. S., Huff, W., Lehnardt, F., Newen, A., & Vogeley, K. (2008). Dissociation between key processes of social cognition in autism: Impaired mentalizing but intact sense of agency. Journal of Autism and Developmental Disorders, 38, 593–605.

    PubMed  Google Scholar 

  • Dawson, G., Meltzoff, A. N., Osterling, J., & Rinaldi, J. (1998). Neuropsychological correlates of early symptoms of autism. Child Development, 69, 1276–1285.

    PubMed  Google Scholar 

  • Dawson, G., Munson, J., Estes, A., Osterling, J., McPartland, J., Toth, K., Carver, L., & Abbott, R. (2002). Neurocognitive function and joint attention ability in young children with autism spectrum disorder versus developmental delay. Child Development, 73, 345–358.

    PubMed  Google Scholar 

  • Di Martino, A., Ross, K., Uddin, L. Q., Sklar, A. B., Castellanos, F. X., & Milham, P. (2009). Functional brain correlates of social and nonsocial processes in autism spectrum disorders: An activation likelihood estimation meta-analysis. Biological Psychiatry, 65, 63–74.

    PubMed  Google Scholar 

  • Diamond, A., & Goldman-Rakic, P. (1989). Comparison of human infants and rhesus monkeys on Piaget’s A not B task: Evidence for dependence on dorsolateral prefrontal cortex. Experimental Brain Research, 74, 24–40.

    Google Scholar 

  • Dichter, G. S., & Belger, A. (2007). Social stimuli interfere with cognitive control in autism. Neuroimage, 35, 1219–1230.

    PubMed  Google Scholar 

  • Dichter, G. S., Radonovich, K. J., Turner-Brown, L. M., Lam, K. S. L., Holtzclaw, Y. N., & Bodfish. J. W. (2009). Performance of children with autism spectrum disorders on the dimension-change card sort task. Journal of Autism and Developmental Disorders. Advance online publication. doi: 10.1007/s10803-009-0886–1.

    Google Scholar 

  • Drewe, E. (1975). Go-no go learning after frontal lobe lesions in humans. Cortex, 11, 8–16.

    PubMed  Google Scholar 

  • Dumontheil, I., Burgess, P. W., & Blakemore, S. J. (2008). Development of rostral prefrontal cortex and cognitive and behavioural disorders. Developmental Medicine and Child Neurology, 50, 168–181.

    PubMed  Google Scholar 

  • Dworzynski, K., Happé, F., Bolton, P., & Ronald, A. (2009). Relationship between symptom domains in autism spectrum disorders: A population based twin study. Journal of Autism and Developmental Disorders, 39, 1197–1210.

    PubMed  Google Scholar 

  • Edgin, J., & Pennington, B. (2005). Spatial cognition in autism spectrum disorders: Superior, impaired, or just intact? Journal of Autism and Developmental Disorders, 35, 729–745.

    PubMed  Google Scholar 

  • Fisher, N., Happé, F., & Dunn, J. (2005). The relationship between vocabulary, grammar, and false belief task performance in children with autistic spectrum disorders and children with moderate learning difficulties. Journal of Child Psychology and Psychiatry, 46, 409–419.

    PubMed  Google Scholar 

  • Folstein, S., & Rutter, M. (1977). Infantile autism: A genetic study of 21 twin pairs. Journal of Child Psychology and Psychiatry, 18, 297–321.

    PubMed  Google Scholar 

  • Fombonne, E., Siddons, F., Achard, S., Frith, U., & Happé, F. (1994). Adaptive behaviour and theory of mind in autism. European Child and Adolescent Psychiatry, 3, 176–186.

    Google Scholar 

  • Frith, U. (1989). Autism: Explaining the enigma. Oxford: Blackwell.

    Google Scholar 

  • Frith, U. (2003). Autism: Explaining the enigma (2nd ed.). Oxford: Blackwell.

    Google Scholar 

  • Frith, U., Happé, F., & Siddons, F. (1994). Autism and theory of mind in everyday life. Social Development, 2, 108–124.

    Google Scholar 

  • Frith, U., & Hermelin, B. (1969). The role of visual and motor cues for normal, subnormal and autistic children. Journal of Child Psychology and Psychiatry, 10, 153–163.

    PubMed  Google Scholar 

  • Frith, U., & Snowling, M. (1983). Reading for meaning and reading for sound in autistic and dyslexic children. British Journal of Developmental Psychology, 1, 329–342.

    Google Scholar 

  • Gallagher, H. L., Happé, F., Brunswick, N., Fletcher, P. C., Frith, U., & Frith, C. D. (2000). Reading the mind in cartoons and stories: An fMRI study of ‘theory of mind’ in verbal and nonverbal tasks. Neuropsychologia, 38, 11–21.

    PubMed  Google Scholar 

  • Geurts, H., Begeer, S., & Stockmann, L. (2009). Brief report: Inhibitory control of socially relevant stimuli in children with high functioning autism. Journal of Autism and Developmental Disorders, 39, 1603–1607.

    PubMed  Google Scholar 

  • Gilbert, S. J., Bird, G., Brindleya, R., Frith, C., & Burgess, P. W. (2008). Atypical recruitment of medial prefrontal cortex in autism spectrum disorders: An fMRI study of two executive function tasks. Neuropsychologia, 46, 2281–2291.

    PubMed  Google Scholar 

  • Gioia, G. A., Isquith, P. K., Guy, S., & Kenworthy, L. (2000). BRIEF: The behavior rating inventory of executive function. Odessa, FL: Psychological Assessment Resources.

    Google Scholar 

  • Goodman, R. (1989). Infantile autism: A syndrome of multiple primary deficits? Journal of Autism and Developmental Disorders, 19, 409–424.

    PubMed  Google Scholar 

  • Griffith, E. M., Pennington, B. F., Wehner, E. A., & Rogers, S. J. (1999). Executive functions in young children with autism. Child Development, 70, 817–832.

    PubMed  Google Scholar 

  • Happé, F. G. E. (1995). The role of age and verbal ability in the theory of mind task performance of subjects with autism. Child Development, 66, 843–855.

    PubMed  Google Scholar 

  • Happé, F. G. E. (1996). Studying weak central coherence at low levels: Children with autism do not succumb to visual illusions. A research note. Journal of Child Psychology and Psychiatry, 37, 873–877.

    PubMed  Google Scholar 

  • Happé, F. G. E. (1997). Central coherence and theory of mind in autism: Reading homographs in context. British Journal of Developmental Psychology, 15, 1–12.

    Google Scholar 

  • Happé, F. (1999). Autism: Cognitive deficit of cognitive style. Trends in Cognitive Sciences, 3, 216–222.

    PubMed  Google Scholar 

  • Happé, F. G. E., Booth, R., Charlton, R., & Hughes, C. (2006). Executive function deficits in autism spectrum disorders and attention-deficit/hyperactivity disorder: Examining profiles across domains and ages. Brain and Cognition, 61, 25–39.

    PubMed  Google Scholar 

  • Happé, F. G. E., & Frith, U. (2006). The weak coherence account: Detail-focused cognitive style in autism spectrum disorders. Journal of Autism and Developmental Disorders, 36, 5–25.

    PubMed  Google Scholar 

  • Happé, F., & Ronald, A. (2008). The ‘fractionable autism triad’: A review of evidence from behavioural, genetic, cognitive and neural research. Neuropsychological Review, 18, 287–304.

    Google Scholar 

  • Happé, F., Ronald, A., & Plomin, R. (2006). Time to give up on a single explanation for autism. Nature Neuroscience, 9, 1218–1220.

    PubMed  Google Scholar 

  • Haviland, J. M., & Lelwica, M. L. (1987). The induced affect response: 10 week-old infants’ responses to three emotional expressions. Developmental Psychology, 23, 97–104.

    Google Scholar 

  • Heaton, R. K. (1981). Wisconsin card sorting test manual. Odessa, FL: Psychological Assessment Resources.

    Google Scholar 

  • Hill, E. L. (2004). Evaluating the theory of executive dysfunction in autism. Developmental Review, 24, 189–233.

    Google Scholar 

  • Hobson, R. P. (1989). Beyond cognition: A theory of autism. In G. Dawson (Ed.), Autism: Nature, diagnosis and treatment (pp. 22–48). New York: Guildford.

    Google Scholar 

  • Hobson, R. P. (1993). Autism and the development of mind. Oxford University Press: Oxford.

    Google Scholar 

  • Hobson, R. P. (2002). The cradle of thought: Exploring the origins of thinking. London: Macmillan.

    Google Scholar 

  • Hockey, A., & Geffen, G. (2004). The concurrent validity and test-retest reliability of a visuospatial working memory task. Intelligence, 32, 591–605.

    Google Scholar 

  • Hoekstra, R. A., Bartels, M., Cath, D. C., & Boomsma, D. I. (2008). Factor structure, reliability and criterion validity of the autism spectrum quotient (AQ): A study in Dutch population and patient groups. Journal of Autism and Developmental Disorders, 38, 1555–1566.

    PubMed  Google Scholar 

  • Hogrefe, G. -J., Wimmer, H., & Perner, J. (1986). Ignorance versus false belief: A developmental lag in attribution of epistemic states. Child Development, 57, 567–582.

    Google Scholar 

  • Hoy, J. A., Hatton, C., & Hare, D. (2004). Weak central coherence: A cross-domain phenomenon specific to autism? Autism, 8, 267–281.

    PubMed  Google Scholar 

  • Hughes, C. H., & Russell, J. (1993). Autistic children’s difficulties with mental disengagement from an object: Its implications for theories of Autism. Developmental Psychology, 29, 498–510.

    Google Scholar 

  • Hughes, C., Russell, J., & Robbins, T. W. (1994). Evidence for executive dysfunction in autism. Neuropsychologia, 32, 477–492.

    PubMed  Google Scholar 

  • Hurst, R. M., Mitchell, J. T., Kimbrel, N. A., Kwapil, T. K., & Nelson-Gray, R. O. (2007). Examination of the reliability and factor structure of the Autism Spectrum Quotient (AQ) in a non-clinical sample. Personality and Individual Differences, 43, 1938–1949.

    Google Scholar 

  • International Molecular Genetic Study of Autism Consortium. (1998). A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Human Molecular Genetics, 7, 571–578.

    Google Scholar 

  • International Molecular Genetic Study of Autism Consortium. (2001). Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q. Human Molecular Genetics, 10, 973–982.

    Google Scholar 

  • International Molecular Genetic Study of Autism Consortium. (2005). Analysis of IMGSAC autism susceptibility loci: Evidence for sex limited and parent origin specific effects. Journal of Medical Genetics, 42, 132–137.

    Google Scholar 

  • Jarrold, C. (2003). A review of research into pretend play in autism. Autism, 7, 379–390.

    PubMed  Google Scholar 

  • Jarrold, C., Gilchrist, I. D., & Bender, A. (2005). Embedded figures detection in autism and typical development: Preliminary evidence of a double dissociation in relationships with visual search. Developmental Science, 8, 344–351.

    PubMed  Google Scholar 

  • Jolliffe, T., & Baron-Cohen, S. (1997). Are people with autism and Asperger syndrome faster than normal on the embedded figures test. Journal of Child Psychology and Psychiatry, 38, 527–534.

    PubMed  Google Scholar 

  • Jolliffe, T., & Baron-Cohen, S. (1999). A test of central coherence theory: Linguistic processing in high-functioning adults with autism or Asperger syndrome: Is local coherence impaired? Cognition, 71, 149–185.

    PubMed  Google Scholar 

  • Jurado, M., & Rosselli, M. (2007). The elusive nature of executive functions: A review of our current understanding. Neuropsychology Review, 17, 213–233.

    PubMed  Google Scholar 

  • Just, M. A., Cherkassky, V. L., Keller, T. A., Kana, R. K., & Minshew, N. J. (2007). Functional and anatomical cortical underconnectivity in autism: Evidence from an fMRI study of an executive function task and corpus callosum morphometry. Cerebral Cortex, 17, 951–961.

    PubMed  Google Scholar 

  • Just, M. A., Cherkassky, V. L., Keller, T. A., & Minshew, N. J. (2004). Cortical activation and synchronization during sentence comprehension in high-functioning autism: Evidence of underconnectivity. Brain, 127, 1811–1821.

    PubMed  Google Scholar 

  • Kaland, N., Mortensen, E. L., & Smith, L. (2007). Disembedding performance in children and adolescents with Asperger syndrome or high-functioning autism. Autism, 11, 81–92.

    PubMed  Google Scholar 

  • Kana, R. K., Keller, T. A., Cherkassky, V. L., Minshew, N. J., & Just, M. A. (2009). Atypical frontal-posterior synchronization of theory of mind regions in autism during mental state attribution. Social Neuroscience, 4, 135–152.

    PubMed  Google Scholar 

  • Kana, R. K., Keller, T. A., Minshew, N. J., & Just, M. A. (2007). Inhibitory control in high-functioning autism: Decreased activation and underconnectivity in inhibition networks. Biological Psychiatry, 62, 198–206.

    PubMed  Google Scholar 

  • Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217–250.

    Google Scholar 

  • Klin, A., Jones, W., Schultz, R., & Volkmar, F. (2003). The enactive mind, or from actions to cognition: Lessons from autism. Philosophical Transactions of the Royal Society B-Biological Sciences, 358, 345–360.

    Google Scholar 

  • Koshino, H., Carpenter, P. A., Minshew, N. J., Cherkassky, V. L., Keller, T. A., & Just, M. A. (2005). Functional connectivity in an fMRI working memory task in high-functioning autism. Neuroimage, 24, 810–821.

    PubMed  Google Scholar 

  • Lam, K. S. L., & Aman, M. G. (2007). The repetitive behavior scale-revised: Independent validation in individuals with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37, 855–866.

    PubMed  Google Scholar 

  • Landa, R. J., & Goldberg, M. C. (2005). Language, social, and executive functions in high functioning autism: A continuum of performance. Journal of Autism and Developmental Disorders, 35, 557–573.

    PubMed  Google Scholar 

  • Leslie, A. M. (1987). Pretense and representation: The origins of theory of mind. Psychological Review, 94, 412–426.

    Google Scholar 

  • Leslie, A. M., & Frith, U. (1990). Prospects for a cognitive neuropsychology of autism: Hobson’s choice. Psychological Review, 97, 122–131.

    PubMed  Google Scholar 

  • Leslie, A. M., & Happé, F. (1989). Autism and ostensive communication: The relevance of metarepresentation. Development and Psychopathology, 1, 205–212.

    Google Scholar 

  • Leslie, A. M., & Roth, D. (1993). What autism teaches us about metarepresentation. In S. Baron-Cohen, H. Tager-Flusberg, & D. Cohen (Eds.), Understanding other minds: Perspectives from autism (pp. 83–111). Oxford: Oxford University Press.

    Google Scholar 

  • Lind, S. E., & Bowler, D. M. (2009). Language and theory of mind in autism spectrum disorder: The relationship between complement syntax and false belief task performance. Journal of Autism and Developmental Disorders, 39, 929–937.

    PubMed  Google Scholar 

  • Lind, S. E., & Bowler, D. M. (2010). Impaired performance on see-know tasks amongst children with autism: Evidence of specific difficulties with theory of mind or domain general task factors? Journal of Autism and Developmental Disorders, 40, 479–484.

    Google Scholar 

  • López, B., & Leekam, S. R. (2003). Do children with autism fail to process information in context? Journal of Child Psychology and Psychiatry, 44, 285–300.

    PubMed  Google Scholar 

  • Lopez, B. R., Lincoln, A. J., Ozonoff, S., & Lai, Z. (2005). Examining the relationship between executive functions and restricted, repetitive symptoms of autistic disorder. Journal of Autism and Developmental Disorders, 35, 445–460.

    PubMed  Google Scholar 

  • Loveland, K. A. (1991). Social affordances and interaction II: Autism and the affordances of the human environment. Ecological Psychology, 3, 99–119.

    Google Scholar 

  • Luna, B., Minshew, N. J., Garver, K. E., Lazar, N. A., Thulborn, K. R., Eddy, W. F., et al. (2002). Neocortical system abnormalities in autism: An fMRI study of spatial working memory. Neurology, 59, 834–840.

    PubMed  Google Scholar 

  • Mandy, W. P. L., & Skuse, D. H. (2008). What is the association between the social-communication element of autism and repetitive interests, behaviours and activities? Journal of Child Psychology and Psychiatry, 49, 795–808.

    PubMed  Google Scholar 

  • McEvoy, R., Rogers, S. J., & Pennington, B. F. (1993). Executive function and social communication deficits in your autistic children. Journal of Child Psychology and Psychiatry, 34, 563–578.

    PubMed  Google Scholar 

  • Morgan, B., Maybery, M., & Durkin, K. (2003). Weak central coherence, poor joint attention, and low verbal ability: Independent deficits in early autism. Developmental Psychology, 39, 646–656.

    PubMed  Google Scholar 

  • Morton, J., & Frith, U. (1995). Causal modeling: A structural approach to developmental psychopathology. In D. Cicchetti & D. J. Cohen (Eds.), Developmental psychopathology, volume 1, theory and methods (pp. 357–390). New York: Wiley.

    Google Scholar 

  • Mottron, L., & Burack, J. A. (2001). Enhanced perceptual functioning in the development of autism. In J. A. Burack, T. Charman, N. Yirmiya, & P. R. Zelazo (Eds.), The development of autism: Perspectives from theory and research (pp. 131–148). Mahwah, NJ: Erlbaum.

    Google Scholar 

  • Mottron, L., Dawson, M., Soulieres, I., Hubert, B., & Burack, J. A. (2006). Enhanced perceptual functioning in autism: An update, and eight principles of autistic perception. Journal of Autism and Developmental Disorders, 36, 27–43.

    PubMed  Google Scholar 

  • Owen, A. M., McMillan, K. M., & Laird, A. R. (2005). N-back working memory paradigm: A meta-analysis of normative functional neuroimaging studies. Human Brain Mapping, 25, 46–59.

    PubMed  Google Scholar 

  • Ozonoff, S., & Jensen, J. (1999). Brief report: Specific executive function profiles in three neurodevelopmental disorders. Journal of Autism and Developmental Disorders, 29, 171–177.

    PubMed  Google Scholar 

  • Ozonoff, S., Pennington, B. F., & Rogers, S. J. (1991). Executive functioning deficits in high-functioning autistic individuals: Relationship to theory of mind. Journal of Child Psychology and Psychiatry, 32, 1081–1105.

    PubMed  Google Scholar 

  • Ozonoff, S., & Strayer, D. L. (2001). Further evidence of intact working memory in autism. Journal of Autism and Developmental Disorders, 31, 257–263.

    PubMed  Google Scholar 

  • Pellicano, E. (2007). Links between theory of mind and executive function in young children with autism: Clues to developmental primacy. Developmental Psychology, 43, 974–990.

    PubMed  Google Scholar 

  • Pellicano, E., Maybery, M., Durkin, K., & Maley, A. (2006). Multiple cognitive capabilities/deficits in children with an autism spectrum disorder: “Weak” central coherence and its relationship to theory of mind and executive control. Development and Psychopathology, 18, 77–98.

    PubMed  Google Scholar 

  • Pennington, B. F., & Ozonoff, S. (1996). Executive functions and developmental psychopathology. Journal of Child Psychology and Psychiatry, 37, 51–87.

    PubMed  Google Scholar 

  • Peterson, C. C., Peterson, J. L., & Webb, J. (2000). Factors influencing the development of a theory of mind in blind children. British Journal of Developmental Psychology, 18, 431–447.

    Google Scholar 

  • Peterson, C. C., & Seigal, M. (1995). Deafness, conversation and theory of mind. Journal of Child Psychology and Psychiatry, 36, 459–474.

    PubMed  Google Scholar 

  • Peterson, C. C., Wellman, H. M., & Lui, D. (2005). Steps in theory-of-mind development for children with deafness or autism. Child Development, 76, 502–517.

    PubMed  Google Scholar 

  • Premack, D., & Woodruff, G. (1978). Does the chimpanzee have a theory of mind? Behavioral and Brain Sciences, 1, 515–526.

    Google Scholar 

  • Ropar, D., & Mitchell, P. (1999). Are individuals with autism and Asperger’s syndrome susceptible to visual illusions? Journal of Child Psychology and Psychiatry, 40, 1283–1293.

    PubMed  Google Scholar 

  • Ropar, D., & Mitchell, P. (2001). Susceptibility to illusions and performance on visuospatial tasks in individuals with autism. Journal of Child Psychology and Psychiatry, 42, 539–549.

    PubMed  Google Scholar 

  • Rumsey, J. M. (1985). Conceptual problem-solving in highly verbal, nonretarded autistic men. Journal of Autism and Developmental Disorders, 15, 23–36.

    PubMed  Google Scholar 

  • Russell, J. (1996). Agency: Its role in mental development. Hove: Lawrence Erlbaum Associates/Taylor and Francis.

    Google Scholar 

  • Russell, J., & Hill, E. L. (2001). Action monitoring and intention reporting in children with autism. Journal of Child Psychology and Psychiatry, 42, 317–328.

    PubMed  Google Scholar 

  • Schlooz, W. A. J. M., Hulstijn, W., van den Broek, P. J. A., van der Pijll, A. C. A. M., Gabreëls, F., van der Gaag, R. J., et al. (2006). Fragmented visuospatial processing in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders, 36, 1025–1037.

    PubMed  Google Scholar 

  • Schmitz, N., Rubia, K., Daly, E., Smith, A., Williams, S., & Murphy, D. G. M. (2006). Neural correlates of executive function in autistic spectrum disorders. Biological Psychiatry, 59, 7–16.

    PubMed  Google Scholar 

  • Senju, A., Southgate, V., White, S., & Frith, U. (2009). Mindblind eyes: An absence of spontaneous theory of mind in Asperger syndrome. Science, 325, 883–885.

    PubMed  Google Scholar 

  • Shah, A., & Frith, U. (1983). An islet of ability in autism: A research note. Journal of Child Psychology and Psychiatry, 24, 613–620.

    PubMed  Google Scholar 

  • Shah, A., & Frith, U. (1993). Why do autistic individuals show superior performance on the block design task? Journal of Child Psychology and Psychiatry, 34, 1351–1364.

    PubMed  Google Scholar 

  • Shallice, T. (1982). Specific impairments in planning. Philosophical Transactions of the Royal Society of London, Series B, 298, 199–209.

    Google Scholar 

  • Siegal, M., & Beattie, K. (1991). Where to look first for children’s knowledge of false beliefs. Cognition, 38, 1–12.

    PubMed  Google Scholar 

  • Sinzig, J., Morsche, P. A., Bruning, N., Schmidt, M. H., & Lehmkuhl, G. (2008). Inhibition, flexibility, working memory and planning in autism spectrum disorders with and without comorbid ADHD-symptoms. Child and Adolescent Psychiatry and Mental Health, 2, 4.

    PubMed  Google Scholar 

  • SLI Consortium. (2004). Highly significant linkage to the SLI1 locus in an expanded sample of individuals affected by specific language impairment. American Journal of Human Genetics, 74, 1225–1238.

    Google Scholar 

  • Sodian, B., & Frith, U. (1992). Deception and sabotage in autistic, retarded and normal children. Journal of Child Psychology and Psychiatry, 33, 591–605.

    PubMed  Google Scholar 

  • South, M., Ozonoff, S., & McMahon, W. M. (2007). The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrum. Autism, 11, 437–451.

    PubMed  Google Scholar 

  • Steele, S. D., Minshew, N. J., Luna, B., & Sweeney, J. A. (2007). Spatial working memory deficits in autism. Journal of Autism and Developmental Disorders, 37, 605–612.

    PubMed  Google Scholar 

  • Steffenburg, S., Hellgren, L. A. L., Gillberg, I. C., Jakobsen, G., & Bohman, M. (1989). A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. Journal of Child Psychology and Psychiatry, 30, 405–416.

    PubMed  Google Scholar 

  • Stewart, M. E., & Austin, E. J. (2009). The structure of the Autism-Spectrum Quotient (AQ): Evidence from a student sample in Scotland. Personality and Individual Differences, 47, 224–228.

    Google Scholar 

  • Stewart, M. E., Watson, J., Allcock, A. –J., & Yaqoob, T. (2009). Autistic traits predict performance on the block design. Autism, 13, 133–142.

    PubMed  Google Scholar 

  • Stroop, J. R. (1935). Studies of interference in serial verbal reactions. Journal of Experimental Psychology, 18, 613–662.

    Google Scholar 

  • Stuss, D. T., Alexander, M. P., Floden, D., Binns, M. A., Levine, B., McIntosh, A. R., et al. (2002). Fractionation and localization of distinct frontal lobe processes: Evidence from focal lesions in humans. In D. T. Stuss & R. T. Knight (Eds.), Principles of frontal lobe function (pp. 392–407). New York: Oxford University Press.

    Google Scholar 

  • Surian, L., & Leslie, A. M. (1999). Competence and performance in false belief understanding: A comparison of autistic and normal 3-year-old children. British Journal of Developmental Psychology, 17, 141–155.

    Google Scholar 

  • Szatmari, P., Merrette, C., Bryson, S. E., Thivierge, J., Roy, M. A., Cayer, M., et al. (2002). Quantifying dimensions in autism: A factor-analytic study. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 467–474.

    Google Scholar 

  • Teunisse, J. -P., Cools, A. R., van Spaendonck, K. P. M., Aerts, F. H., & Berger, H. J. (2001). Cognitive styles in high-functioning adolescents with autistic disorder. Journal of Autism and Developmental Disorders, 31, 55–66.

    PubMed  Google Scholar 

  • Turner, M. (1999). Repetitive behaviour in autism: A review of psychological research. Journal of Child Psychology and Psychiatry, 40, 839–849.

    PubMed  Google Scholar 

  • Wechsler, D. (2004). Wechsler intelligence scale for children (4th UK ed.). London: Harcourt Assessment.

    Google Scholar 

  • Wellman, H., Cross, D., & Watson, J. (2001). Meta-analysis of theory of mind development: The truth about false belief. Child Development, 72, 655–684.

    PubMed  Google Scholar 

  • Williams, D. L., Goldstein, G., Carpenter, P. A., & Minshew, N. J. (2005). Verbal and spatial working memory in autism. Journal of Autism and Developmental Disorders, 35, 747–756.

    PubMed  Google Scholar 

  • Williams, D. M., & Happé, F. (2009a). What did I say? versus What did I think?: Attributing false beliefs to self amongst children with and without autism. Journal of Autism and Developmental Disorders, 39, 865–873.

    PubMed  Google Scholar 

  • Williams, D., & Happé, F. (2009b). Pre-conceptual aspects of self-awareness in autism spectrum disorder: The case of action monitoring. Journal of Autism and Developmental Disorders, 39, 251–259.

    PubMed  Google Scholar 

  • Williams, D. M., & Happé, F. (2010). Representing intentions in self and others: Studies of autism and typical development. Developmental Science, 13, 307–319.

    Google Scholar 

  • Williams, D. M. (2010). Theory of own mind in autism: Evidence of a specific deficit in self-awareness? Autism, 14, 474–494.

    Google Scholar 

  • Williams, D. M., Lind, S. E., & Happé, F. G. E. (2009). Metacognition may be more impaired than mindreading in autism. Behavioral and Brain Sciences, 32, 162–163.

    Google Scholar 

  • Wimmer, H., & Perner, J. (1983). Beliefs about beliefs: Representation and constraining function of wrong beliefs in young children’s understanding of deception. Cognition, 13, 103–128.

    PubMed  Google Scholar 

  • Wing, L., & Gould, J. (1979). Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification. Journal of Autism and Childhood Schizophrenia, 9, 11–29.

    Google Scholar 

  • Witkin, H. A., Oltman, P. K., Raskin, E., & Karp, S. (1971). A manual for the embedded figures test. Palo Alto, CA: Consulting Psychologists Press.

    Google Scholar 

  • Wolpert, D. M., Ghahramani, Z., & Jordan, M. I. (1995). An internal model for sensorimotor integration. Science, 269, 1880–1882.

    PubMed  Google Scholar 

  • World Health Organization. (1993). International classification of diseases (10th ed.). Geneva: World Health Organization.

    Google Scholar 

  • Yirmiya, N., Erel, O., Shaked, M., & Solomonica-Levi, D. (1998). Meta-analyses comparing theory of mind abilities of individuals with autism, individuals with mental retardation, and normally developing individuals. Psychological Bulletin, 124, 283–307.

    PubMed  Google Scholar 

  • Zilbovicius, M., Meresse, I., Chabane, N., Brunelle, F., Samson, Y., et al. (2006). Autism, the superior temporal sulcus and social perception. Trends in Neuroscience, 29, 359–366.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sophie E. Lind .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Lind, S.E., Williams, D.M. (2011). Behavioural, Biopsychosocial, and Cognitive Models of Autism Spectrum Disorders. In: Matson, J., Sturmey, P. (eds) International Handbook of Autism and Pervasive Developmental Disorders. Autism and Child Psychopathology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8065-6_7

Download citation

Publish with us

Policies and ethics