Abstract
Autism has been described as a lifelong disorder that emerges in the first year or two of life (Kanner, 1943). Whereas Kanner’s longitudinal assessment of his original cohort (Kanner & Eisenberg, 1956) and the few follow-up studies that have been conducted through to adulthood suggest a generally stable diagnosis, recent literature challenges the notion that autism is definitively stable in all individuals diagnosed earlier in life. Prior studies indicate that most individuals diagnosed with autism continue to exhibit symptoms, whether profound or residual, through developmental stages; however, specific information about patterns of symptom change continues to be limited. In part, this is because research focused on examining symptomatology over the life course is inherently impeded by changes in diagnostic methodology, limitations of currently available assessment technology (particularly for older individuals), and other factors that may influence our ability to measure changes in the presentation of autism symptoms over time. This chapter explores the extant literature on symptom presentation across various developmental stages, ranging from onset during infancy, patterns of onset that include developmental regression, preschool through school-age years, and the adolescent/adulthood period. The chapter will focus on autistic disorder, but will consider the fuller spectrum that includes pervasive developmental disorder, not otherwise specified (PDD-NOS) and Asperger syndrome (AS), particularly in the discussion of diagnostic stability. The term autism spectrum disorders (ASD) will be used when collectively referencing this group of disorders.
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References
Achenbach, T. (1991). Manual for the child behavior checklist/4-18 and 1991 profile. Burlington, VT: Department of Psychiatry of the University of Vermont.
Achenbach, T., & Edelbrock, C. (1983). Manual for the child behavior checklist and revised child behavior profile. Burlington, VT: Department of Psychiatry of the University of Vermont.
Anderson, D. K., Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., et al. (2007). Patterns of growth in verbal abilities among children with autism spectrum disorder. Journal of Consulting and Clinical Psychology, 75, 594–604.
Anderson, D. K., Oti, R. S., Lord, C., & Welch, K. (2009). Patterns of growth in adaptive social abilities among children with autism spectrum disorders. Journal of Abnormal Child Psychology, 37, 1019–1034.
Baranek, G. T. (1999). Autism during infancy: A retrospective video analysis of sensory-motor and social behaviors at 9–12 months of age. Journal of Autism and Developmental Disorders, 29, 213–224.
Begovac, I., Begovac, B., Majic, G., & Vidovic, V. (2009). Longitudinal studies of IQ stability in children with childhood autism – Literature survey. Psychiatr Danub, 21, 310–319.
Bennett, T., Szatmari, P., Bryson, S., Volden, J., Zwaigenbaum, L., Vaccarella, L., et al. (2008). Differentiating autism and Asperger syndrome on the basis of language delay or impairment. Journal of Autism and Developmental Disorders, 38, 616–625.
Billstedt, E., & Gillberg, C. (2005). Autism after adolescence: Population-based 13- to 22-year follow-up study of 120 individuals with autism diagnosed in childhood. Journal of Autism and Developmental Disorders, 35, 351–360.
Billstedt, E., Gillberg, I. C., & Gillberg, C. (2005). Autism in adults: Symptom patterns and early childhood predictors. Use of the DISCO in a community sample followed from childhood. Journal of Child Psychology and Psychiatry and Allied Disciplines, 48, 1102–1110.
Bishop, S., Richler, J., & Lord, C. (2006). Association between restricted and repetitive behaviors and nonverbal IQ in children with autism spectrum disorders. Child Neuropsychology (Neuropsychology, Development and Cognition: Section C), 12(4), 247–267.
Bruner, J. (1981). The social context of language acquisition. Language and Communication, 1, 155–178.
Burack, J. A., Pasto, L., Poporino, M., Iarocci, G., Mottron, L., & Bowler, D. (2001). Applying developmental principles to the study of autism. In E. Schopler, N. Yirmiya, C. Shulman, & L. M. Marcus (Eds.), The research basis for autism intervention (pp. 25–38). New York: Kluwer Academic.
Carpenter, M., Nagell, K., Tomasello, M., Butterworth, G., & Moore, C. (1998). Social cognition, joint attention, and communicative competence from 9 to 15 months of age. Monographs of the Society for Research in Child Development, 63.
CDC (2009). Prevalence of autism spectrum disorders – autism and developmental disabilities monitoring network, United States, 2006. MMWR, 58, 1–20.
Charman, T., Baron-Cohen, S., Swettenham, J., Baird, G., Drew, A., & Cox, A. (2003). Predicting language outcome in infants with autism and pervasive developmental disorder. International Journal of Language and Communication Disorders, 38, 265–285.
Charman, T., Taylor, E., Drew, A., Cockerill, H., Brown, J. A., & Baird, G. (2005). Outcome at 7 years of children diagnosed with autism at age 2: Predictive validity of assessments conducted at 2 and 3 years of age and pattern of symptom change over time. Journal of Child Psychology and Psychiatry and Allied Disciplines, 46, 500–513.
Chawarska, K., Klin, A., Paul, R., Macari, S., & Volkmar, F. (2009). A prospective study of toddlers with ASD: Short-term diagnostic and cognitive outcomes. Journal of Child Psychology and Psychiatry and Allied Disciplines, 50, 1235–1245.
Constantino, J. N., Gruber, C. P., Davis, S., Hayes, S., Passanante, N., & Przybeck, T. (2004). The factor structure of autistic traits. Journal of Child Psychology and Psychiatry and Allied Disciplines, 45, 719–726.
Coonrod, E. E., & Stone, W. L. (2004). Early concerns of parents of children with autistic and nonautistic disorders. Infants & Young Children, 17, 258–268.
Cox, A., Klein, K., Charman, T., Baird, G., Baron-Cohen, S., Swettenham, J., et al. (1999). Autism spectrum disorders at 20 and 42 months of age: Stability of clinical and ADI-R diagnosis. Journal of Child Psychology and Psychiatry and Allied Disciplines, 40, 719–732.
Davidovitch, M., Glick, L., Holtzman, G., Tirosh, E., & Safir, M. (2000). Developmental regression in autism: Maternal perception. Journal of Autism and Developmental Disorders, 30, 113–119.
Dawson, G. (2008). Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder. Development and Psychopathology, 20, 775–803.
Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., et al. (2010). Randomized, controlled trial of an intervention for toddlers with autism: The early start Denver model. Pediatrics, 125, 17–23.
Dawson, G., Toth, K., Abbott, R., Osterling, J., Munson, J., Estes, A., et al. (2004). Early social attention impairments in autism: Social orienting, joint attention, and attention to distress. Developmental Psychology, 40, 271–283.
Esbensen, A., Bishop, S., Seltzer, M., Greenberg, J., & Taylor, J. (2010). Comparisons between individuals with autism spectrum disorders and individuals with down syndrome in adulthood. Intellectual and Developmental Disabilities, 115, 277–290.
Esbensen, A. J., Seltzer, M. M., Lam, K. S., & Bodfish, J. W. (2009). Age-related differences in restricted repetitive behaviors in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 57–66.
Estes, A. M., Dawson, G., Sterling, L., & Munson, J. (2007). Level of intellectual functioning predicts patterns of associated symptoms in school-age children with autism spectrum disorder. [Journal; Peer Reviewed Journal]. American Journal on Mental Retardation, 112, 439–449.
Fombonne, E. (2005). Epidemiology of autistic disorder and other pervasive developmental disorders. Journal of Clinical Psychiatry, 66(Suppl 10), 3–8.
Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2004). Psychiatric symptoms in preschool children with PDD and clinic and comparison samples. Journal of Autism and Developmental Disorders, 34, 379–393.
Gillberg, C., & Steffenburg, S. (1987). Outcome and prognostic factors in infantile autism and similar conditions: A population-based study of 46 cases followed through puberty. Journal of Autism and Developmental Disorders, 17(2), 273–287.
Goldberg, W., Osann, K., Filipek, P., Laulhere, T., Jarvis, K., Modahl, C., et al. (2003). Language and other regression: Assessment and timing. Journal of Autism and Developmental Disorders, 33, 607–616.
Gotham, K., Pickles, A., & Lord, C. (2009). Standardizing ADOS scores for a measure of severity in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 693–705.
Gotham, K., Risi, S., Pickles, A., & Lord, C. (2007). The autism diagnostic observation schedule: Revised algorithms for improved diagnostic validity. Journal of Autism and Developmental Disorders, 37, 613–627.
Granpeesheh, D., Tarbox, J., Dixon, D. R., Carr, E., & Herbert, M. (2009). Retrospective analysis of clinical records in 38 cases of recovery from autism. Annals of Clinical Psychiatry, 21, 195–204.
Helt, M., Kelley, E., Kinsbourne, M., Pandey, J., Boorstein, H., Herbert, M., et al. (2008). Can children with autism recover? If so, how? Neuropsychology Review, 18, 339–366.
Honey, E., Leekam, S., Turner, M., & McConachie, H. (2007). Repetitive behaviour and play in typically developing children and children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37, 1107–1115.
Howlin, P., Goode, S., Hutton, J., & Rutter, M. (2004). Adult outcome for children with autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 45, 212–229.
Hutton, J., Goode, S., Murphy, M., Le Couteur, A., & Rutter, M. (2008). New-onset psychiatric disorders in individuals with autism. Autism, 12, 373–390.
Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217–250.
Kanner, L., Eisenberg, L. (1956). Early infantile autism. American Journal of Orthopsychiatry, 26, 55–65.
Kaufman, J., Martin, A., King, R. A., & Charney, D. (2001). Are child-, adolescent-, and adult-onset depression one and the same disorder? Biological Psychiatry, 49, 980–1001.
Kjelgaard, M., & Tager-Flusberg, H. (2001). An investigation of language impairment in autism: Implications for genetic subgroups. Language and Cognitive Processes, 16, 287.
Kobayashi, R., & Murata, T. (2003). Behavioral characteristics of 187 young adults with autism. Psychiatry and Clinical Neurosciences, 52, 383–390.
Lam, K. S., & Aman, M. G. (2007). The repetitive behavior scale-revised: Independent validation in individuals with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37, 855–866.
Landa, R., & Garrett-Mayer, E. (2006). Development in infants with autism spectrum disorders: A prospective study. Journal of Child Psychology and Psychiatry and Allied Disciplines, 47, 629–638.
Leekam, S., Tandos, J., McConachie, H., Meins, E., Parkinson, K., Wright, C., et al. (2007). Repetitive behaviours in typically developing 2-year-olds. Journal of Child Psychology and Psychiatry and Allied Disciplines, 48, 1131–1138.
Lord, C. (1995). Follow-up of two-year-olds referred for possible autism. Journal of Child Psychology and Psychiatry, 36, 1365–1382.
Lord, C., & Risi, S. (2000). Diagnosis of autism spectrum disorder in young children. In A. M. Wetherby & B. M. Prizant (Eds.), Autism spectrum disorders: A transactional developmental perspective (pp. 11–30). Baltimore: Brookes.
Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., & Pickles, A. (2006). Autism from 2 to 9 years of age. Archives of General Psychiatry, 63, 694–701.
Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.
Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.
Lord, C., Wagner, A., Rogers, S., Szatmari, P., Aman, M., Charman, T., et al. (2005). Challenges in evaluating psychosocial interventions for autistic spectrum disorders. Journal of Autism and Developmental Disorders, 35, 695–708.
Luyster, R., Richler, J., Risi, S., Hsu, W., Dawson, G., Bernier, R., et al. (2005). Early regression in social communication in autism spectrum disorders: A CPEA study. Developmental Neuropsychology, 27, 311–336.
Matson, J. L., Hess, J. A., Neal, D., Mahan, S., Fodstad, J. C. (2010). Trend in symptoms in children diagnosed with autistic disorder as measured by the Autism Spectrum Disorders-Diagnostic for Children (ASD-DC). Journal of Developmental and Physical Disabilities, 22, 47–56.
Moore, V., & Goodson, S. (2003). How well does early diagnosis of autism stand the test of time? Follow-up study of children assessed for autism at age 2 and development of an early diagnostic service. Autism, 7, 47–63.
Morgan, L., Wetherby, A. M., & Barber, A. (2008). Repetitive and stereotyped movements in children with autism spectrum disorders late in the second year of life. Journal of Child Psychology and Psychiatry and Allied Disciplines, 49, 826–837.
Mundy, P., Sigman, M., & Kasari, C. (1990). A longitudinal study of joint attention and language development in autistic children. Journal of Autism and Developmental Disorders, 20, 115–128.
Mundy, P., Sigman, M., & Kasari, C. (1994). Joint attention, developmental level, and symptom presentation in autism. Development and Psychopathology, 6, 389–401.
Munson, J., Faja, S., Meltzoff, A., Abbott, R., & Dawson, G. (2008). Neurocognitive predictors of social and communicative developmental trajectories in preschoolers with autism spectrum disorders. Journal of the International Neuropsychological Society, 14, 956–966.
Ozonoff, S., Heung, K., Byrd, R., Hansen, R., & Hertz-Picciotto, I. (2008). The onset of autism: Patterns of symptom emergence in the first years of life. Autism Research, 1, 320–328.
Ozonoff, S., Williams, B. J., & Landa, R. (2005). Parental report of the early development of children with regressive autism: The delays-plus-regression phenotype. Autism, 9, 461–486.
Ozonoff, S., Young, G., Steinfeld, M., Hill, M., Cook, I., Hutman, T., et al. (2009). How early do parent concerns predict later autism diagnosis? Journal of Developmental and Behavioral Pediatrics, 30, 367.
Pearson, D. A., Loveland, K. A., Lachar, D., Lane, D. M., Reddoch, S. L., Mansour, R., et al. (2006). A comparison of behavioral and emotional functioning in children and adolescents with autistic disorder and PDD-NOS. Child Neuropsychology, 12, 321–333.
Perry, A., Flanagan, H. E., Dunn Geier, J., & Freeman, N. L. (2009). Brief report: The Vineland Adaptive Behavior scales in young children with autism spectrum disorders at different cognitive levels. Journal of Autism and Developmental Disorders, 39, 1066–1078.
Rapin, I. (2003). Value and limitations of preschool cognitive tests, with an emphasis on longitudinal study of children on the autistic spectrum. Brain and Development, 25, 546–548.
Richler, J., Bishop, S. L., Kleinke, J. R., & Lord, C. (2007). Restricted and repetitive behaviors in young children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37, 73–85.
Richler, J., Huerta, M., Bishop, S. L., & Lord, C. (2010). Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders. Developmental Psychopathology, 22(1), 55–69.
Richler, J., Luyster, R., Risi, S., Hsu, W., Dawson, G., Bernier, R., et al. (2006). Is there a ‘regressive phenotype’ of autism spectrum disorder associated with the measles-mumps-rubella vaccine? A CPEA study. Journal of Autism and Developmental Disorders, 36, 299–316.
Rogers, S. J. (2009). What are infant siblings teaching us about autism in infancy? Autism Research, 2, 125–137.
Rutter, M., Greenfield, D., & Lockyer, L. (1967). A five-to-fifteen-year follow-up study of infantile psychosis: II. Social and behavioral outcome. British Journal of Psychiatry, 113, 1183–1199.
Seltzer, M., Shattuck, P., Abbeduto, L., & Greenberg, J. (2004). Trajectory of development in adolescents and adults with autism. Mental Retardation and Developmental Disabilities Research Reviews, 10, 234–247.
Shattuck, P. T., Seltzer, M. M., Greenberg, J. S., Orsmond, G. I., Bolt, D., Kring, S., et al. (2007). Change in autism symptoms and maladaptive behaviors in adolescents and adults with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1735–1747.
Short, A. B., & Schopler, E. (1988). Factors relating to age of onset in autism. Journal of Autism and Developmental Disorders, 18, 207–216.
Shumway, S., & Wetherby, A. M. (2009). Communicative acts of children with autism spectrum disorders in the second year of life. Journal of Speech, Language, and Hearing Research, 52, 1139–1156.
Sigman, M., & McGovern, C. (2005). Improvement in cognitive and language skills from preschool to adolescence in autism. Journal of Autism and Developmental Disorders, 35, 15–23.
Sigman, M., & Ruskin, E. (1999a). Continuity and change in the social competence of children with autism, Down syndrome and developmental delays. Monographs of the Society for Research in Child Development, 64, 1–114.
Sigman, M., & Ruskin, E. (1999b). Social competence in children with autism, Down syndrome and developmental delays: A longitudinal study. Monographs of the Society for Research in Child Development, 64.
Siller, M., & Sigman, M. (2008). Modeling longitudinal change in the language abilities of children with autism: Parent behaviors and child characteristics as predictors of change. Developmental Psychology, 44, 1691–1704.
Sparrow, S., Balla, D., & Cicchetti, D. V. (1984). Vineland adaptive behavior scales. Circle Pines, MN: American Guidance Service, Inc.
Stone, W., Lee, E. B., Ashford, L., Brissie, J., Hepburn, S. L., Coonrod, E. E., et al. (1999). Can autism be diagnosed accurately in children under 3 years? Journal of Child Psychology and Psychiatry, 40, 219–226.
Szatmari, P., Bryson, S. E., Boyle, M. H., Streiner, D. L., & Duku, E. (2003). Predictors of outcome among high functioning children with autism and Asperger syndrome. Journal of Child Psychology and Psychiatry and Allied Disciplines, 44, 520–528.
Szatmari, P., Bryson, S., Duku, E., Vaccarella, L., Zwaigenbaum, L., Bennett, T., et al. (2009). Similar developmental trajectories in autism and Asperger syndrome: From early childhood to adolescence. Journal of Child Psychology and Psychiatry and Allied Disciplines, 50, 1459–1467.
Tager-Flusberg, H., Rogers, S., Cooper, J., Landa, R., Lord, C., Paul, R., et al. (2009). Defining spoken language benchmarks and selecting measures of expressive language development for young children with autism spectrum disorders. Journal of Speech, Language, and Hearing Research, 52, 643–652.
Thomas, M. S., Annaz, D., Ansari, D., Scerif, G., Jarrold, C., & Karmiloff-Smith, A. (2009). Using developmental trajectories to understand developmental disorders. Journal of Speech, Language, and Hearing Research, 52, 336–358.
Thurm, A., Lord, C., Lee, L. C., & Newschaffer, C. (2007). Predictors of language acquisition in preschool children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37, 1721–1734.
Tomanik, S., Pearson, D., Loveland, K., Lane, D., & Bryant Shaw, J. (2007). Improving the reliability of autism diagnoses: Examining the utility of adaptive behavior. Journal of Autism and Developmental Disorders, 37, 921–928.
Turner, L. M., & Stone, W. L. (2007). Variability in outcome for children with an ASD diagnosis at age 2. Journal of Child Psychology and Psychiatry and Allied Disciplines, 48, 793–802.
Turner, L. M., Stone, W. L., Pozdol, S. L., & Coonrod, E. E. (2006). Follow-up of children with autism spectrum disorders from age 2 to age 9. Autism, 10, 243–265.
Venter, A., Lord, C., & Schopler, E. (1992). A follow-up of high-functioning autistic children. Journal of Child Psychology and Psychiatry, 33, 489–507.
Volkmar, F., Klin, A., Siegel, B., Szatmari, P., Lord, C., Campbell, M., et al. (1994). Field trial for autistic disorder in DSM-IV. American Journal of Psychiatry, 151, 1361.
Volkmar, F. R., & Nelson, D. S. (1990). Seizure disorders in autism. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 127–129.
Watt, N., Wetherby, A. M., Barber, A., & Morgan, L. (2008). Repetitive and stereotyped behaviors in children with autism spectrum disorders in the second year of life. Journal of Autism and Developmental Disorders, 38, 1518–1533.
Werner, E., & Dawson, G. (2005). Validation of the phenomenon of autistic regression using home videotapes. Archives of General Psychiatry, 62, 889–895.
Werner, E., Dawson, G., Munson, J., & Osterling, J. (2005). Variation in early developmental course in autism and its relation with behavioral outcome at 3–4 years of age. Journal of Autism and Developmental Disorders, 35, 337–350.
Werner, E., Dawson, G., Osterling, J., & Dinno, N. (2000). Brief report: Recognition of autism spectrum disorder before one year of age: A retrospective study based on home videotapes. Journal of Autism and Developmental Disorders, 30, 157–162.
Wetherby, A., Prizant, B., & Hutchinson, T. (1998). Communicative, social/affective, and symbolic profiles of young children with autism and pervasive developmental disorders. American Journal of Speech-Language Pathology, 7, 79.
Wetherby, A. M., Watt, N., Morgan, L., & Shumway, S. (2007). Social communication profiles of children with autism spectrum disorders late in the second year of life. Journal of Autism and Developmental Disorders, 37, 960–975.
Wetherby, A. M., Woods, J., Allen, L., Cleary, J., Dickinson, H., & Lord, C. (2004). Early indicators of autism spectrum disorders in the second year of life. Journal of Autism and Developmental Disorders, 34, 473–493.
Wing, L. (1983). Social and interpersonal needs. In E. Schopler, & G. B. Mesibov (Eds.), Autism in adolescents and adults (pp. 337–354). New York: Plenum Press.
Young, G. S., Merin, N., Rogers, S. J., & Ozonoff, S. (2009). Gaze behavior and affect at 6 months: Predicting clinical outcomes and language development in typically developing infants and infants at risk for autism. Developmental Science, 12, 798–814.
Zwaigenbaum, L., Bryson, S., Lord, C., Rogers, S., Carter, A., Carver, L., et al. (2009). Clinical assessment and management of toddlers with suspected autism spectrum disorder: Insights from studies of high-risk infants. Pediatrics, 123, 1383–1391.
Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005). Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience, 23, 143–152.
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Thurm, A., Bishop, S., Shumway, S. (2011). Developmental Issues and Milestones. In: Matson, J., Sturmey, P. (eds) International Handbook of Autism and Pervasive Developmental Disorders. Autism and Child Psychopathology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8065-6_10
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