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Soft Tissue and Bone Tumors

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Handbook of Practical Immunohistochemistry

Abstract

Immunohistochemistry is a powerful adjunctive technique for the pathologic diagnosis of soft tissue and bone tumors, although some tumors still lack specific markers. This chapter includes the questions about the immunohistochemical markers for normal soft tissue and bone, soft ­tissue and bone tumors, and their utility for differentiation. The questions are answered in the form of tables. The photos of selected markers are also included. New markers such as MDM2, TLS/EWS-CHOP chimeric oncoproteins, HHV8, TFE3, and TLE1, as well as other commonly used markers, are discussed.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA

    Shaobo Zhu

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  1. Shaobo Zhu
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  2. Markku Miettinen
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Correspondence to Shaobo Zhu .

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  1. , Pathology and Laboratory Medicine, Geisinger Health System, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Fan Lin

  2. , Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Jeffrey Prichard

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Zhu, S., Miettinen, M. (2011). Soft Tissue and Bone Tumors. In: Lin, F., Prichard, J. (eds) Handbook of Practical Immunohistochemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8062-5_26

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