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Handbook of Practical Immunohistochemistry pp 277–298Cite as

Ovary

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Abstract

Although the majority of ovarian tumors are ­diagnosed purely on morphologic findings, this chapter identifies specific opportunities for the application of immunohistochemistry to the diagnosis of ovarian surface epithelial tumors, sex cord–stromal tumors, and germ cells tumors. This chapter addresses the use of newer markers such as SALL4 in yolk sac tumors and PAX8 in serous, clear cell and endometrioid carcinomas. Special attention is paid to ovarian versus appendiceal mucinous tumors in pseudomyxoma peritonei, metastatic Krukenberg tumors, and the differential diagnosis of primary and metastatic clear cell tumors. Illustrations demonstrate differential staining patterns such as is seen with p16 in müllerian tumors.

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  1. Department of Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA

    Jeffrey Prichard

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  1. Jeffrey Prichard
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  2. Haiyan Liu
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  3. Myra Wilkerson
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Correspondence to Jeffrey Prichard .

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  1. , Pathology and Laboratory Medicine, Geisinger Health System, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Fan Lin

  2. , Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Jeffrey Prichard

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© 2011 Springer Science+Business Media, LLC

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Prichard, J., Liu, H., Wilkerson, M. (2011). Ovary. In: Lin, F., Prichard, J. (eds) Handbook of Practical Immunohistochemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8062-5_17

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  • DOI: https://doi.org/10.1007/978-1-4419-8062-5_17

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  • Online ISBN: 978-1-4419-8062-5

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