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Echinoderm Immunity

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Invertebrate Immunity

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 708))

Abstract

A survey for immune genes in the genome for the purple sea urchin has shown that the immune system is complex and sophisticated. By inference, immune responses of all echinoderms may be similar. The immune system is mediated by several types of coelomocytes that are also useful as sensors of environmental stresses. There are a number of large gene families in the purple sea urchin genome that function in immunity and of which at least one appears to employ novel approaches for sequence diversification. Echinoderms have a simpler complement system, a large set of lectin genes and a number of antimicrobial peptides. Profiling the immune genes expressed by coelomocytes and the proteins in the coelomic fluid provide detailed information about immune functions in the sea urchin. The importance of echinoderms in maintaining marine ecosystem stability and the disastrous effects of their removal due to disease will require future collaborations between ecologists and immunologists working towards understanding and preserving marine habitats.

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Authors and Affiliations

  1. Department of Biological Sciences, George Washington University, Washington DC, USA

    L. Courtney Smith, Julie Ghosh, Cheng Man Lun, Audrey J. Majeske, Sandro Sacchi & Catherine S. Schrankel

  2. Department of Medical Biophysics and Department of Immunology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

    Katherine M. Buckley & Jonathan P. Rast

  3. US Patent and Trademark Office, Alexandria, Virginia, USA

    Lori A. Clow

  4. Department of Biological Sciences, Macquarie University, Sydney, Australia

    Nolwenn M. Dheilly, Sham V. Nair, David A. Raftos & Mattias Roth

  5. Norwegian College of Fishery Science, University of Tromso, Tromso, Norway

    Tor Haug, Chun Li & Klara Stensvåg

  6. Department of Biology and the Biochemistry and Molecular Biology Program, Dickinson College, Carlisle, Pennsylvania, USA

    John H. Henson

  7. CNR, Institute of Biomedicine and Molecular Immunology “Albert Monroy”, Palermo, Italy

    Valeria Matranga

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Smith, L.C. et al. (2010). Echinoderm Immunity. In: Söderhäll, K. (eds) Invertebrate Immunity. Advances in Experimental Medicine and Biology, vol 708. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8059-5_14

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