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Antioxidants and Skin

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Nutrition and Skin

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References

  • Akaike T. Role of free radicals in viral pathogenesis and mutation. Rev Med Virol. 2001;11:87–101.

    Article  PubMed  CAS  Google Scholar 

  • Aust O, Stahl W, Sies H, Tronnier H, Heinrich U. Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema. Int J Vitam Nutr Res. 2005;75:54–60.

    Article  PubMed  CAS  Google Scholar 

  • Biesalski HK, Obermueller-Jevic UC. UV light, beta-carotene and human skin-beneficial and potentially harmful effects. Arch Biochem Biophys. 2001;389:1–6.

    Article  PubMed  CAS  Google Scholar 

  • Black HS. Potential involvement of free radical reactions in ultraviolet light-mediated cutaneous damage. Photochem Photobiol. 1987;46:213–21.

    Article  PubMed  CAS  Google Scholar 

  • Burke KE, Wei H. Synergistic damage by UVA radiation and pollutants. Toxicol Ind Health. 2009;25:219–24.

    Article  PubMed  CAS  Google Scholar 

  • Cesarini JP, Michel L, Maurette JM, Adhoute H, Bejot M. Immediate effects of UV radiation on the skin: modification by an antioxidant complex containing carotenoids. Photodermatol Photoimmunol Photomed. 2003;19:182–9.

    Article  PubMed  CAS  Google Scholar 

  • Darvin ME, Gersonde I, Albrecht H, Gonchukov SA, Sterry W, Lademann J. Determination of beta carotene and lycopene concentrations in human skin using resonance Raman spectroscopy. Laser Phys. 2005a;15:295–9.

    CAS  Google Scholar 

  • Darvin ME, Gersonde I, Meinke M, Sterry W, Lademann J. Non-invasive in vivo determination of the carotenoids beta-carotene and lycopene concentrations in the human skin using the Raman spectroscopic method. J Phys D Appl Phys. 2005b;38:2696–700.

    Article  CAS  Google Scholar 

  • Darvin M, Zastrow L, Sterry W, Lademann J. Effect of supplemented and topically applied antioxidant substances on human tissue. Skin Pharmacol Physiol. 2006;19:238–47.

    Article  PubMed  CAS  Google Scholar 

  • Darvin ME, Gersonde I, Albrecht H, Sterry W, Lademann J. Resonance Raman spectroscopy for the detection of carotenolds in foodstuffs. Influence of the nutrition on the antioxidative potential of the skin. Laser Phys Lett. 2007;4:452–6.

    Article  CAS  Google Scholar 

  • Darvin ME, Patzelt A, Knorr F, Blume-Peytavi U, Sterry W, Lademann J. One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors. J Biomed Opt. 2008a;13:044028.

    Article  PubMed  Google Scholar 

  • Darvin M, Patzelt A, Gehse S, Schanzer S, Benderoth C, Sterry W, et al. Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. Eur J Pharm Biopharm. 2008b;69:943–7.

    Article  PubMed  CAS  Google Scholar 

  • Darvin ME, Haag S, Meinke M, Zastrow L, Sterry W, Lademann J. Radical production by infrared A irradiation in human tissue. Skin Pharmacol Physiol. 2010a;23:40–6.

    Article  PubMed  CAS  Google Scholar 

  • Darvin ME, Haag SF, Lademann J, Zastrow L, Sterry W, Meinke MC. Formation of free radicals in human skin during irradiation with infrared light. J Invest Dermatol. 2010b;130:629–31.

    Article  PubMed  CAS  Google Scholar 

  • Dhalla NS, Temsah RM, Netticadan T. Role of oxidative stress in cardiovascular diseases. J Hypertens. 2000;18:655–73.

    Article  PubMed  CAS  Google Scholar 

  • Dinkova-Kostova AT. Phytochemicals as protectors against ultraviolet radiation: versatility of effects and mechanisms. Planta Med. 2008;74(13):1548–59.

    Article  PubMed  CAS  Google Scholar 

  • Dreher F, Maibach H. Protective effects of topical antioxidants in humans. Curr Probl Dermatol. 2001;29:157–64.

    Article  PubMed  CAS  Google Scholar 

  • Droge W. Free radicals in the physiological control of cell function. Physiol Rev. 2002;82:47–95.

    PubMed  CAS  Google Scholar 

  • Gallicchio L, Boyd K, Matanoski G, Tao XG, Chen L, Lam TK, et al. Carotenoids and the risk of developing lung cancer: a systematic review. Am J Clin Nutr. 2008;88:372–83.

    PubMed  CAS  Google Scholar 

  • Gartner C, Stahl W, Sies H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr. 1997;66:116–22.

    PubMed  CAS  Google Scholar 

  • Halliwell B. Biochemistry of oxidative stress. Biochem Soc Trans. 2007;35:1147–50.

    Article  PubMed  CAS  Google Scholar 

  • Halvorsen BL, Holte K, Myhrstad MC, Barikmo I, Hvattum E, Remberg SF, et al. A systematic screening of total antioxidants in dietary plants. J Nutr. 2002;132:461–71.

    PubMed  CAS  Google Scholar 

  • Heinrich U, Gartner C, Wiebusch M, Eichler O, Sies H, Tronnier H, et al. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. J Nutr. 2003;133:98–101.

    PubMed  CAS  Google Scholar 

  • Heinrich U, Neukam K, Tronnier H, Sies H, Stahl W. Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women. J Nutr. 2006a;136(6):1565–9.

    PubMed  CAS  Google Scholar 

  • Heinrich U, Tronnier H, Stahl W, Bejot M, Maurette JM. Antioxidant supplements improve parameters related to skin structure in humans. Skin Pharmacol Physiol. 2006b;19:224–31.

    Article  PubMed  CAS  Google Scholar 

  • Hsu S. Green tea and the skin. J Am Acad Dermatol. 2005;52(6):1049–59.

    Article  PubMed  Google Scholar 

  • Iannone A, Marconi A, Zambruno G, Giannetti A, Vannini V, Tomasi A. Free-radical production during metabolism of organic hydroperoxides by normal human keratinocytes. J Invest Dermatol. 1993;101:59–63.

    Article  PubMed  CAS  Google Scholar 

  • Jackson MJ. Free radicals in skin and muscle: damaging agents or signals for adaptation? Proc Nutr Soc. 1999;58:673–6.

    Article  PubMed  CAS  Google Scholar 

  • Katiyar SK, Perez A, Mukhtar H. Green tea polyphenol treatment to human skin prevents formation of ultraviolet light B-induced pyrimidine dimers in DNA. Clin Cancer Res. 2000;6(10):3864–9.

    PubMed  CAS  Google Scholar 

  • Kawaguchi Y, Tanaka H, Okada T, Konishi H, Takahashi M, Ito M, et al. Effect of reactive oxygen species on the elastin mRNA expression in cultured human dermal fibroblasts. Free Radic Biol Med. 1997;23:162–5.

    Article  PubMed  CAS  Google Scholar 

  • Lademann J, Patzelt A, Darvin M, Richter H, Antoniou C, Sterry W, et al. Application of optical non-invasive methods in skin physiology. Laser Phys Lett. 2008;5:335–46.

    Article  CAS  Google Scholar 

  • Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistry (Mosc). 1998;63:854–65.

    CAS  Google Scholar 

  • Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. Polyphenols: food sources and bioavailability. Am J Clin Nutr. 2004;79(5):727–47.

    PubMed  CAS  Google Scholar 

  • Monboisse JC, Borel JP. Oxidative damage to collagen. EXS. 1992;62:323–7.

    PubMed  CAS  Google Scholar 

  • Neukam K, Stahl W, Tronnier H, Sies H, Heinrich U. Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin. Eur J Nutr. 2007;46(1):53–6.

    Article  PubMed  CAS  Google Scholar 

  • Nichols JA, Katiyar SK. Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res. 07 November 2009. doi: 10.1007/s00403-00901001-1. PubMed PMID: 1989885

    Google Scholar 

  • Palmer DM, Kitchin JS. Oxidative damage, skin aging, antioxidants and a novel antioxidant rating system. J Drugs Dermatol. 2010;9:11–5.

    PubMed  Google Scholar 

  • Paolini M, bdel-Rahman SZ, Sapone A, Pedulli GF, Perocco P, Cantelli-Forti G, et al. beta-Carotene: a cancer chemopreventive agent or a co-carcinogen? Mutat Res. 2003;543:195–200.

    Article  PubMed  CAS  Google Scholar 

  • Rivero A. Nitric oxide: an antiparasitic molecule of invertebrates. Trends Parasitol. 2006;22:219–25.

    Article  PubMed  CAS  Google Scholar 

  • Roques C, Teot L, Frasson N, Meaume S. PRIMOS: an optical system that produces three-­dimensional measurements of skin surfaces. J Wound Care. 2003;12:362–4.

    PubMed  CAS  Google Scholar 

  • Sander CS, Chang H, Hamm F, Elsner P, Thiele JJ. Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis. Int J Dermatol. 2004;43:326–35.

    Article  PubMed  CAS  Google Scholar 

  • Schroeder P, Lademann J, Darvin ME, Stege H, Marks C, Bruhnke S, et al. Infrared radiation-induced matrix metalloproteinase in human skin: implications for protection. J Invest Dermatol. 2008;128:2491–7.

    Article  PubMed  CAS  Google Scholar 

  • Schroeder P, Calles C, Benesova T, Macaluso F, Krutmann J. Photoprotection beyond ultraviolet radiation–effective sun protection has to include protection against infrared A radiation-induced skin damage. Skin Pharmacol Physiol. 2010;23:15–7.

    Article  PubMed  CAS  Google Scholar 

  • Sies H, Stahl W. Nutritional protection against skin damage from sunlight. Annu Rev Nutr. 2004;24:173–200.

    Article  PubMed  CAS  Google Scholar 

  • Stahl W, Heinrich U, Jungmann H, von LJ, Schietzel M, Sies H, et al. Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting Betatene. J Nutr. 1998;128:903–7.

    PubMed  CAS  Google Scholar 

  • Stevenson DE, Hurst RD. Polyphenolic phytochemicals–just antioxidants or much more? Cell Mol Life Sci. 2007;64(22):2900–16.

    Article  PubMed  CAS  Google Scholar 

  • Talwar D, Ha TK, Cooney J, Brownlee C, O’Reilly DS. A routine method for the simultaneous measurement of retinol, alpha-tocopherol and five carotenoids in human plasma by reverse phase HPLC. Clin Chim Acta. 1998;270:85–100.

    Article  PubMed  CAS  Google Scholar 

  • Woodall AA, Lee SWM, Weesie RJ, Jackson MJ, Britton G. Oxidation of carotenoids by free radicals: relationship between structure and reactivity. Biochim Biophys Acta. 1997;1336:33–42.

    PubMed  CAS  Google Scholar 

  • Wrona M, Korytowski W, Rozanowska M, Sarna T, Truscott TG. Cooperation of antioxidants in protection against photosensitized oxidation. Free Radic Biol Med. 2003;35:1319–29.

    Article  PubMed  CAS  Google Scholar 

  • Yusuf N, Irby C, Katiyar SK, Elmets CA. Photoprotective effects of green tea polyphenols. Photodermatol Photoimmunol Photomed. 2007;23(1):48–56.

    Article  PubMed  Google Scholar 

  • Zastrow L, Groth N, Klein F, Kockott D, Lademann J, Renneberg R, et al. The missing link–light-induced (280–1,600 nm) free radical formation in human skin. Skin Pharmacol Physiol. 2009;22:31–44.

    Article  PubMed  CAS  Google Scholar 

  • Zhang P, Omaye ST. Antioxidant and prooxidant roles for beta-carotene, alpha-tocopherol and ascorbic acid in human lung cells. Toxicol In Vitro. 2001;15:13–24.

    Article  PubMed  Google Scholar 

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Correspondence to Juergen Lademann .

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Lademann, J., Darvin, M.E., Heinrich, U. (2011). Antioxidants and Skin. In: Pappas, A. (eds) Nutrition and Skin. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7967-4_6

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