Acne affects 80–90% of individuals during puberty, which is a period associated with a normal decline in insulin sensitivity (Bloch et al, J Pediatr 110:481–487, 1987). Hyperinsulinemia stemming from insulin resistance may play a key role in activating a hormonal milieu conducive for acne development.
Acne remains relatively unknown among non-Westernized societies existing on low-glycemic-load diets, and prevalence rates increase when a previously unaffected society is exposed to refined, high-glycemic-index carbohydrates.
Low-glycemic-load diets may represent a unique dietary strategy for alleviating acne symptoms through improving insulin metabolism.
KeywordsPlacebo Cholesterol Sugar Obesity Depression
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