Adhesion-GPCRs pp 179-188 | Cite as

Adhesion-GPCRs in the Male Reproductive Tract

  • Ben Davies
  • Christiane Kirchhoff
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 706)


The male reproductive tract expresses a diverse array of adhesion-GPCRs, many in a highly specific and regulated manner. Despite this specificity of expression, little is known about the function of this receptor family in male reproductive physiology. Insights into function are beginning to emerge with the increasing availability of genetically modified mice harbouring mutations in these genes. Gpr64 is the best characterised of the adhesion-GPCRs in the male reproductive system and the phenotype of Gpr64 knock-out mice implicates this receptor in the regulation of fluid absorption in the efferent ducts and proximal epididymis. This chapter summarizes recent data concerning this receptor and other family members in the male reproductive system.


Male Reproductive System Germ Cell Development Male Reproductive Tract Efferent Duct Taste Receptor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Ben Davies
    • 1
  • Christiane Kirchhoff
  1. 1.Wellcome Trust Centre for Human GeneticsUniversity of OxfordRoosevelt DriveUK

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