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High-Dose Chemotherapy and Stem Cell Transplantation for Primary CNS Lymphoma

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Lymphoma and Leukemia of the Nervous System

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Abstract

The treatment of patients with CNS lymphoma has posed a challenge since this entity was first described. Several issues have complicated the management of these patients. First, it is important to define whether the lymphoma is confined to the CNS (primary CNS lymphoma, PCNSL) or whether there is co-existent or pre-existent systemic lymphoma (stage IV or secondary CNS lymphoma, respectively). Second, it is important to define the histological subtypes of lymphoma involving the CNS since multiple histologies are known to occur in the CNS and the treatment can vary depending on the histology.

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Author information

Authors and Affiliations

  1. Service d’Hématologie, Centre de Lutte Contre le Cancer René Huguenin, Saint-Cloud, France

    Carole Soussain

  2. Division of Hematology, Department of Medicine, Mayo Clinic Graduate School of Medicine, Rochester, MN, USA

    Patrick Johnston

  3. Department of Haematology and Oncology, University Medical Center Freiburg, Freiburg, Germany

    Gerald Illerhaus

Authors
  1. Carole Soussain
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  2. Patrick Johnston
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  3. Gerald Illerhaus
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Corresponding author

Correspondence to Carole Soussain .

Editor information

Editors and Affiliations

  1. , Stephen E. and Catherine Pappas Center f, Massachusetts General Hospital, Fruit St. 55, Boston, 02114, Massachusetts, USA

    Tracy Batchelor

  2. Dept. Neurology, Memorial Sloan-Kettering Cancer Center, York Ave. 1275, New York, 10021-6007, New York, USA

    Lisa M. DeAngelis

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Soussain, C., Johnston, P., Illerhaus, G. (2012). High-Dose Chemotherapy and Stem Cell Transplantation for Primary CNS Lymphoma. In: Batchelor, T., DeAngelis, L. (eds) Lymphoma and Leukemia of the Nervous System. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7668-0_9

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