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CNS Post-Transplant Lymphoproliferative Disorder

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Lymphoma and Leukemia of the Nervous System

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Abstract

Post-transplant lymphoproliferative disorders (PTLDs) were first recognized in 1968 and central nervous system (CNS) PTLD in 1970 [1]. They arise in both solid organ and bone marrow/stem cell transplant recipients. The causative role of Epstein-Barr virus (EBV) was quickly recognized, although not all PTLD is EBV-driven.

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Author information

Authors and Affiliations

  1. Clinical Head, Lymphoma Service, Middlemore Hospital, Auckland, New Zealand

    Samar Issa

  2. Division of Neuropathology, Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA, 22908-0214, USA

    M. Beatriz S. Lopes

  3. Departments of Neurology, Neurological Surgery and Medicine, School of Medicine, University of Virginia, Charlottesville, VA, 22908-0214, USA

    David Schiff

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  1. Samar Issa
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  2. M. Beatriz S. Lopes
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  3. David Schiff
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Correspondence to David Schiff .

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Editors and Affiliations

  1. , Stephen E. and Catherine Pappas Center f, Massachusetts General Hospital, Fruit St. 55, Boston, 02114, Massachusetts, USA

    Tracy Batchelor

  2. Dept. Neurology, Memorial Sloan-Kettering Cancer Center, York Ave. 1275, New York, 10021-6007, New York, USA

    Lisa M. DeAngelis

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Issa, S., Lopes, M.B.S., Schiff, D. (2012). CNS Post-Transplant Lymphoproliferative Disorder. In: Batchelor, T., DeAngelis, L. (eds) Lymphoma and Leukemia of the Nervous System. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7668-0_11

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