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Nanoelectronics for DNA Sensing

  • Predrag S. Krstić
Chapter
Part of the Nanostructure Science and Technology book series (NST)

Abstract

The human genome sequencing is the fastest developing field of the contemporary science, possibly offering significant contribution to the personalized medicine–a cheap and fast tabletop single molecule reading device on a chip. This can be achieved with physical methods, based on the reading of an electrical response while a segment of a DNA molecule is passing through a synthetic nanopore. The challenges, and possible solutions to the problems of sensitivity of the electrical reading as well as to the control of a DNA localization and motion are considered.

Keywords

Tunneling Current Resonant Tunneling Paul Trap Quadrupole Trap Linear Paul Trap 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This research was supported by the U.S. National Human Genome Research Institute of the National Institutes of Health under grant no. 1R21HG004764-01. The author acknowledges support by U.S. Department of Energy (DOE) at ORNL managed by a UT-Battelle for the U.S. DOE under contract no. DEAC05-00OR22725, by the U.S. DOE, and U.S. NHGRI under grant no. 1 R21 HG003578-01. A portion of this research was conducted at the Center for Nanophase Materials Sciences, which is sponsored at ORNL by the Division of Scientific User Facilities, U.S. DOE.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Physics DivisionOak Ridge National LaboratoryOak RidgeUSA

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