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DNA-Based Nanotechnology Biosensors for Surgical Diagnosis

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Nanotechnology Enabled In situ Sensors for Monitoring Health

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Abstract

This chapter covers the use of DNA in biological sensing devices. Although DNA has been used for a number of years for in vitro sensing applications, there are several unique challenges to using DNA as in vivo sensors. This chapter covers some of the more significant advances in this field highlighting how these challenges are being met. In doing so, it emphasizes various ways DNA can be immobilized to implants to sense implant functionality. It also emphasizes various forms of DNA highlighting the advantages and disadvantages for in vivo sensor applications.

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Authors and Affiliations

  1. Department of Orthopaedics, School of Engineering, Brown University, 184 Hope Street, Providence, RI, 02917, USA

    Yupeng Chen

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  1. Yupeng Chen
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  2. Hongchuan Yu
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Correspondence to Yupeng Chen .

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Editors and Affiliations

  1. School of Engineering, Brown University, 182 Hope Street, Providence, 02912, Rhode Island, USA

    Thomas J. Webster

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Chen, Y., Yu, H. (2011). DNA-Based Nanotechnology Biosensors for Surgical Diagnosis. In: Webster, T. (eds) Nanotechnology Enabled In situ Sensors for Monitoring Health. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7291-0_4

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  • DOI: https://doi.org/10.1007/978-1-4419-7291-0_4

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