Abstract
Ketenimines are a class of versatile and highly reactive intermediates that can participate in a variety of organic reactions, such as nucleophilic additions, radical additions, [2 + 2] and [2 + 4] cycloadditions, and sigmatropic rearrangements. In this presentation, we report on a series of multi-component reactions that involve a ketenimine intermediate. These reactions could furnish diverse heterocyclic compounds, including functionalized iminocoumarin, iminodihydroqunolines, iminothiochromens, pyrrolines, isoquinolines, pyridines, β-lactams, imino-1,2-dihydrocoumarins, and benzimidazoles.
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Acknowledgment
P. Lu thanks the National Nature Science Foundation of China (20674070). Contributions from Prof. Shengming Ma and Prof. Jinquan Yu in mechanism postulation and Jianming Gu and Xiurong Wu in structure elucidation are greatly appreciated.
This study was supported by the Programme for the Support of Leading Scientific Schools (grant no. 3758.2008.3).
Our research has been performed with the financial support of the grant of the President of Russian Federation no. MK-2198.2008.3.
This work was supported by the Presidium of the Russian Academy of Sciences (coordinator: academician V. A. Tartakovsky).
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Wang, Y. et al. (2011). Novel Reagents for Multi-Component Reactions. In: Mironov, M. (eds) MCR 2009. Advances in Experimental Medicine and Biology, vol 699. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7270-5_4
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DOI: https://doi.org/10.1007/978-1-4419-7270-5_4
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