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The Angiogenic Switch: Role of Immune Cells

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Immunologic Signatures of Rejection

Abstract

Angiogenesis is a frequent hallmark of inflammation; in acute inflammation angiogenesis occurs to revascularize damaged tissues, with subsequent vascular pruning and maturation, which results in restoration of an adequate blood supply to the tissue involved. Angiogenesis is also a characteristic of chronic inflammation, and may be one of the links between inflammation and cancer (Colotta et al. 2009; Kobayashi and Lin 2009).

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Acknowledgements

These studies were supported by grants from the AIRC (Associazione Italiana per la Ricerca sul Cancro), the Istituto Superiore della Sanità Alleanza contro il Cancro foundation, the Ministero della Sanità Progetto Finalizzato, the MIUR Progetto Finalizzato and FIRB, the Università degli studi dell’Insubria and the Compagnia di San Paolo. AV is the recipient of a FIRB (Fondazione Italiana per la Ricerca sul Cancro) fellowship, AB and AP are in the Molecular and Cellular Biology PhD program of the University of Insubria.

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    Douglas M. Noonan

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Noonan, D.M., Ventura, A., Bruno, A., Pagani, A., Albini, A. (2011). The Angiogenic Switch: Role of Immune Cells. In: Marincola, F., Wang, E. (eds) Immunologic Signatures of Rejection. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7219-4_5

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