Rational Approach to Pediatric Antifungal Therapy

  • William J. SteinbachEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 697)


To begin a rational approach to the treatment of pediatric invasive fungal infections, one has to first correctly diagnose the infections. While this is not the focus of this review, the critical nature of the correct diagnosis cannot be overemphasized. For instance, medically important fungi can be generally divided into yeasts and molds, and often that simplistic delineation is the only result the clinician will have for many days while the microbiology laboratory is fully identifying the pathogen. However, even this initial distinction can be crucial to beginning empiric antifungal therapy in the highest risk patients. While a yeast infection can largely include Candida, Cryptococcus, or Trichosporon species, a mold infection is more complicated as they can be further subdivided into septate and aseptate (without hyphal septa).


Antifungal Therapy Invasive Aspergillosis Invasive Fungal Infection Invasive Candidiasis Liposomal Amphotericin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Pediatrics, Division of Pediatric Infectious DiseasesDuke UniversityDurhamUSA
  2. 2.Department of Molecular Genetics and MicrobiologyDuke UniversityDurhamUSA
  3. 3.International Pediatric Fungal NetworkDuke University Medical CenterDurhamUSA

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