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Physiologic Changes in Cardiac Function with Aging

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Abstract

Age-related changes in the cardiovascular system, overt and occult cardiovascular disease, and decreased physical activity affect cardiovascular function in older persons. With aging, there is a loss of myocytes in both the left and right ventricles with a progressive increase in myocyte cell volume per nucleus in both ventricles [1]. There is also a progressive decrease in the number of pacemaker cells in the sinus node, with only 10% of the number of cells present at age 20 remaining at age 75 [2].

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Aronow, W.S., Frishman, W.H. (2011). Physiologic Changes in Cardiac Function with Aging. In: Rosenthal, R., Zenilman, M., Katlic, M. (eds) Principles and Practice of Geriatric Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6999-6_50

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