Physiologic Changes in Cardiac Function with Aging



Age-related changes in the cardiovascular system, overt and occult cardiovascular disease, and decreased physical activity affect cardiovascular function in older persons. With aging, there is a loss of myocytes in both the left and right ventricles with a progressive increase in myocyte cell volume per nucleus in both ventricles [1]. There is also a progressive decrease in the number of pacemaker cells in the sinus node, with only 10% of the number of cells present at age 20 remaining at age 75 [2].


Placebo Radionuclide Cardiomyopathy Catecholamine Digoxin 


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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Cardiology DivisionNew York Medical CollegeValhallaUSA

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