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Principles and Practice of Geriatric Surgery pp 69–82Cite as

Hematological Changes, Anemia, and Bleeding in Older Persons

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Abstract

Age-related changes in the human hematopoietic system are subtle, are often difficult to separate from coexistent comorbidities, and are of clinical import under conditions that stress hematopoiesis. Anemia is the most common age-related hematologic abnormality, and in the elderly surgical patient, proper management of disorders of hemostasis and thrombosis is particularly important. These are covered in detail in the chapter that follows. Marrow disorders such as myelodysplasia (MDS), acute myeloid leukemia (AML), monoclonal gammopathies (MG), polycythemia vera (PV), essential thrombocythemia (ET), and idiopathic myelofibrosis (IMF), all of which have a predilection for the elderly, are also discussed.

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Author information

Authors and Affiliations

  1. Division of Hematology/Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Bruce O. Hough

Authors
  1. Bruce O. Hough
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  2. Gurkamal S. Chatta
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Correspondence to Bruce O. Hough .

Editor information

Editors and Affiliations

  1. School of Medicine, Department of Surgery, Yale University, New Haven, 06520, Connecticut, USA

    Ronnie Ann Rosenthal

  2. Downstate Medical Center, State University of New York, Clarkson Ave. 450, Brooklyn, 11203, New York, USA

    Michael E. Zenilman

  3. , Chairman, Department of Surgery, Sinai Hospital, 2401 West Belvedere Avenue, Baltimore, 21215, Maryland, USA

    Mark R. Katlic

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Hough, B.O., Chatta, G.S. (2011). Hematological Changes, Anemia, and Bleeding in Older Persons. In: Rosenthal, R., Zenilman, M., Katlic, M. (eds) Principles and Practice of Geriatric Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6999-6_5

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  • DOI: https://doi.org/10.1007/978-1-4419-6999-6_5

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  • Online ISBN: 978-1-4419-6999-6

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