Cytology of Normal/Reactive Lymph Nodes

  • Stefan E. Pambuccian
  • Ricardo H. Bardales
Part of the Essentials in Cytopathology book series (EICP, volume 10)


The goal of a lymph node FNA is essentially to distinguish benign from malignant lymphoid processes. Non-neoplastic disorders that can manifest in lymph nodes include those with specific diagnoses and nonspecific reactive hyperplasia (the most common diagnosis). The role of FNA is paramount in determining the etiology of non-neoplastic disorders so that appropriate management can be instituted.


Germinal Center Hodgkin Lymphoma Sezary Syndrome Castleman Disease Reactive Lymphoid Hyperplasia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Flanders E, Kornstein MJ et al (1993) Lymphoglandular bodies in fine-needle aspiration cytology smears. Am J Clin Pathol 99(5):566–569PubMedGoogle Scholar
  2. Harris NL (2001) Mature B-cell neoplasms. Introduction, pathology and genetics. In: Jaffe ES, Harris NL, Stein H, Vardiman JW (eds) WHO classification of tumors of the haematopoietic and lymphoid tissues. IARC Press, Lyon, pp 121–126Google Scholar
  3. Ioachim HL, Medeiros LJ (2009) The normal lymph node. In: Ioachim H, Medeiros LJ (eds) Ioachim’s lymph node pathology, 4th edn. Lippincott Williams & Wilkins, Philadelphia, pp 2–14Google Scholar
  4. Jaffe ES, Harris NL, Stein H, Vardiman JW (2001) Tumors of haematopoietic and lymphoid tissue. WHO-IARC Press, LyonGoogle Scholar
  5. Kurtin PJ (2000) Marginal zone B cells, monocytoid B cells, and the follicular microenvironment. Determinants of morphologic features in a subset of low-grade B-cell lymphomas. Am J Clin Pathol 114(4):505–508PubMedCrossRefGoogle Scholar
  6. Stein H (1999) Lymphocyte differentiation. In: Mason DY, Harris NL (eds) Human lymphoma: clinical implications of the REAL classification. Springer, New YorkGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Lab. Medicine & PathologyUniversity of MinnesotaMinneapolisUSA
  2. 2.Outpatient Pathology AssociatesSacramentoUSA

Personalised recommendations