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Oral Therapy for Bladder Pain Syndrome Directed at the Bladder

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Bladder Pain Syndrome

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Abstract

Initial oral therapy for BPS can include amitriptyline, cimetidine, hydroxyzine, and/or pentosan polysulfate sodium. Cyclosporine should be reserved for use by experienced clinicians after less potentially morbid alternatives have been exhausted. Few of the oral therapies commonly used for the treatment of BPS have unequivocal evidence of efficacy in large, multicenter, randomized controlled clinical trials. There is little evidence that any change the natural history of the disease, though many seem to be effective in relieving symptoms in individual patients. Tachyphylaxis may be a problem.

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Authors and Affiliations

  1. Division of Surgery, Department of Urology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

    Philip M. Hanno M.D., M.P.H.

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  1. Philip M. Hanno M.D., M.P.H.
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Correspondence to Philip M. Hanno M.D., M.P.H. .

Editor information

Editors and Affiliations

  1. University of Copenhagen, Department of Urology, Herlev Hospital, Herlev, 2730, Denmark

    Jørgen Nordling

  2. University Hospital Antwerp, Department of Urology, and Antwerp University, Edegem, 2650, Belgium

    Jean Jacques Wyndaele

  3. and Internal Medicine, Erasmus MC,, Departments of Immunology, University Medical Center Rotterdam, Rotterdam, 3141 XW, Netherlands

    Joop P. van de Merwe

  4. Koege Hospital, Department of Clinical Biochemistry, University of Copenhagen, Copenhagen, 4600, Denmark

    Pierre Bouchelouche

  5. Department Obstetrics and Gynecology, Department of Urogynecology S.Carlo-IDI, Catholic University, Rome, 00165, Italy

    Mauro Cervigni

  6. Institute of Clinical Sciences, Department of Urology, Sahlgrens Academy at University of Gothenburg, Göteborg, 41345, Sweden

    Magnus Fall

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Hanno, P.M. (2013). Oral Therapy for Bladder Pain Syndrome Directed at the Bladder. In: Nordling, J., Wyndaele, J., van de Merwe, J., Bouchelouche, P., Cervigni, M., Fall, M. (eds) Bladder Pain Syndrome. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6929-3_21

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  • DOI: https://doi.org/10.1007/978-1-4419-6929-3_21

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