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Inherited Cancer Syndromes pp 181–196Cite as

Hereditary Ovarian Cancer and Other Gynecologic Malignancies

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Abstract

Although the majority of gynecologic malignancies are sporadic, there is a subset of patients who develop genetic forms of gynecologic cancer. Advances in molecular biology have allowed for an understanding of the physiological pathways of development of inherited gynecologic malignancies and the identification of genetic alterations that lead to the malignant phenotype. The aim of this chapter is to help the clinician identify those patients who are at risk for developing inherited forms of gynecologic malignancies and who would benefit from screening, chemoprevention, and surgery.

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Authors and Affiliations

  1. Department of Obstetrics, Gynecology and Women’s Health, University of Louisville Hospital, Louisville, KY, 40202, USA

    Kathryn R. Brown & Lynn P. Parker

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  1. Kathryn R. Brown
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  2. Lynn P. Parker
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Correspondence to Kathryn R. Brown .

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  1. , Colon and Rectal Surgery, West Penn Allegheny Health System, East North Avenue 320, Pittsburgh, 15212, Pennsylvania, USA

    C. Neal Ellis

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Brown, K.R., Parker, L.P. (2011). Hereditary Ovarian Cancer and Other Gynecologic Malignancies. In: Ellis, C. (eds) Inherited Cancer Syndromes. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6821-0_10

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  • DOI: https://doi.org/10.1007/978-1-4419-6821-0_10

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