Closed-loop Bio-signal Amplifiers: Experimental Results



In this chapter, we will present the measurement results of the telescopic-cascode and complementary low-noise amplifiers discussed in the previous chapter. In order to compare and contrast the performance of these two LNA designs, we fabricated both LNAs in a 0.13 μm CMOS process. As the analog front-end of a neuralrecording channel, each LNA is followed with a variable-gain amplifier (VGA) to accommodate signals of various amplitudes. Fig. 5.1 illustrates one recording channel with the complementary LNA followed by a VGA.


Dition Kelly Bide 


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  1. [1]
    Denison T, Consoer K, Santa W, Avestruz A, Cooley J, Kelly A (2009) A 2mW 100nV/rtHz chopper-stabilized instrumentation amplifier for chronic measurement of neural field potentials. IEEE J Solid-State Circuits 42(12):2934–2945CrossRefGoogle Scholar
  2. [2]
    Harison R, Charles C (2003) A low-power low-noise CMOS amplifier for neural recording applications. IEEE J Solid-State Circuits 38(6):958–956 CrossRefGoogle Scholar
  3. [3]
    Holleman J, Otis B (2007) A sub-microwatt low-noise amplifier for neural recording. In: 29th annual international conference of the IEEE Engineering in Medicine and Biology Society (EMBS 2007), Lyon, pp 3930–3933Google Scholar
  4. [4]
    Wattanapanitch W, Fee M, Sarpeshkar R (2007) An energy-efficient micropower neural recording amplifier. IEEE Trans Biomed CircuitsSyst 1(2):136–147CrossRefGoogle Scholar
  5. [5]
    Wu H, Xu Y (2006) A 1V 2.3mW biomedical signal acquisition IC. In: Proceedings of the 2006 IEEE international conference on solid-state circuits, Digest of Technical Papers, San Francisco, CA, pp 119–128Google Scholar

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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Electrical Engineering and Computer ScienceUniversity of TennesseeKnoxvilleUSA
  2. 2.Department of Electrical EngineeringUniversity of WashingtonSeattleUSA

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