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Potential Neuroprotective Strategies for Traumatic Brain Injury

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Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases

Abstract

Traumatic brain injury (TBI) is caused by physical trauma to the brain tissue that temporarily or permanently impairs brain function. According to Centers for Disease Control and Prevention about 2 million people sustain a TBI in the USA each year, of which approximately 70,000–90,000 suffer from long-term disability (Nolan, 2005). Symptoms and severity of a TBI can be mild, moderate, or severe depending on the intensity of impact and extent of the damage to the brain. Some TBI symptoms appear immediately, while others do not appear until several days or weeks. Mild TBI symptoms include headache, confusion, lightheadedness, dizziness, blurred vision, fatigue, and trouble with memory (Bahraini et al., 2009). Moderate TBI produces a headache that gets worse with time, seizures, inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, loss of coordination, increased confusion.

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  1. Department of Molecular and Cellular Biochemistry, The Ohio State University, 1645 Neil Avenue, Columbus, OH, 43210, USA

    Akhlaq A. Farooqui

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Farooqui, A.A. (2010). Potential Neuroprotective Strategies for Traumatic Brain Injury. In: Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6652-0_7

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