Adrenal Tumors



When one thinks of adrenal tumors in children, neuroblastoma is usually the first consideration. However, there are several other neoplastic processes that can involve the adrenal gland in the pediatric population and run the gamut from aggressive malignancies with a very poor prognosis to benign processes with an excellent prognosis. They might be completely asymptomatic or express a broad variety of endocrine behaviors. Although heterogeneous by nature, they share the fact that surgery is the primary mode of therapy.


Adrenal Tumor Adrenal Mass Adrenocortical Carcinoma Adrenal Vein Adrenocortical Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Bugg MF, Ribeiro RC, Roberson PK, et al. Correlation of pathologic features with clinical outcome in pediatric adrenocortical neoplasia. Am J Clin Pathol. 1994;101:625–9.PubMedGoogle Scholar
  2. Michalkiewicz E, Sandrini R, Figueiredo B, et al. Clinical and outcome characteristics of children with adrenocortical tumors. An analysis of 254 cases from the International Pediatric Adrenocortical Tumor Registry. J Clin Oncol. 2004;22:838–45.CrossRefPubMedGoogle Scholar
  3. Rescorla FJ. Malignant adrenal tumors. Semin Pediatr Surg. 2006;15:48–56.CrossRefPubMedGoogle Scholar
  4. Sullivan J, Groshong T, Tobias JD. Presenting signs and symptoms of pheochromocytoma in pediatric-aged patients. Clin Pediatr (Phila). 2005;44(44):715.CrossRefGoogle Scholar
  5. Zancanella P, Pianovski MA, Oliveira BH, Ferman S, Piovezan GC, Lichtvan LL, et al. Mitotane associated with cisplatin, etoposide, and doxorubicin in advanced childhood adrenocortical carcinoma: mitotane monitoring and tumor regression. J Pediatr Hematol Oncol. 2006;28:513–24.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Pediatric SurgeryUniversity of North Carolina, North Carolina Medical HospitalChapel HillUSA

Personalised recommendations