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Intestinal Transplantation

  • Thomas M. Fishbein
Chapter

Abstract

Intestinal transplantation is increasingly accepted as standard therapy for patients who develop intestinal and parenteral nutrition failure. While early attempts at intestinal transplantation more than 40 years ago met with limited success, progress has led to clinical success that parallels other solid-organ transplants. Intestinal transplants are now performed for children who suffer a failure of gut function from a variety of causes. In such cases, the state of nutritional failure is irreversible and no other therapy can guarantee long-term survival. In rare instances, gut function can be preserved, but anatomical defects, such as congenital malformation or mesenteric tumors require exenteration in order to preserve life. Thus, candidates fail parenteral nutrition, cannot adapt to life on parenteral nutrition, or require removal of the native gut in order to survive.

Keywords

Parenteral Nutrition Superior Mesenteric Artery Short Bowel Syndrome Intestinal Transplantation Intestinal Failure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Transplant InstituteGeorgetown University HospitalWashingtonUSA

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