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Fungal Infections in Solid Organ Transplant Recipients

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Abstract

Organ transplantation is an effective life-sparing modality for thousands of patients with organ failure syndromes. In spite of important advances in surgical technique and immunosuppressive regimens that have made organ transplantation a safer procedure today when compared to previous decades, there remain substantial risks of infection and other complications related to these procedures. Among the infectious complications of organ transplantation, none is associated with a greater impact on morbidity and mortality than invasive fungal infections (IFI) [1–5]. Fungal infections in organ transplant recipients (OTRs) vary in frequency, etiology, and pathogenesis according to the type of organ transplant procedure. Variations in immunosuppressive regimens, surgical technique, infection control, and exposure history further complicate evaluation of these patients. Moreover, the incidence of IFIs among this group of patients varies considerably from center to center [6].

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  1. Division of Infectious Diseases, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA

    Peter G. Pappas

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  1. Veterans Affairs Ann Arbor Healthcare, Professor of Internal Medicine, University of Michigan Medical School, 2215 Fuller Road, Ann Arbor, 48105, Michigan, USA

    Carol A. Kauffman

  2. Division of Infectious Diseases, University of Alabama at Birmingham, 1900 University Blvd., Birmingham, 35294, Alabama, USA

    Peter G. Pappas

  3. Division of Infectious Diseases, Wayne State University School of Medicin, 3990 John R Street, Detroit, 48201, Michigan, USA

    Jack D. Sobel

  4. School of Medicine, Professor Emeritus of Medicine, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, 35294, Alabama, USA

    William E. Dismukes

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Pappas, P.G. (2011). Fungal Infections in Solid Organ Transplant Recipients. In: Kauffman, C., Pappas, P., Sobel, J., Dismukes, W. (eds) Essentials of Clinical Mycology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6640-7_30

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