• Heikki J. JärvinenEmail author
  • Jukka-Pekka Mecklin
Part of the M.D. Anderson Solid Tumor Oncology Series book series (MDA, volume 5)


In Lynch syndrome surveillance aims at prevention of early detection of cancer types observed to occur in significant excess. At present, regular prophylactic examinations have been shown beneficial for colorectal and endometrial cancer, i.e. repeated colonoscopy and endometrial biopsy combined with ultrasonograpy. For other less common cancer types involved, no proven benefit has been shown. The guidelines of identifying Lynch syndrome, the principles of genetic testing, and arranging surveillance are reviewed in this article, also shortly dealing with prophylactic surgery and possible chemoprevention in future.


Colonoscopy Colorectal carcinoma Endometrial carcinoma Lynch syndrome Cancer prevention Polypectomy Endometrial biopsy Prophylactic surgery 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of SurgeryHelsinki University Central HospitalHelsinkiFinland

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