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FAP-Associated Desmoid Tumours

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Hereditary Colorectal Cancer

Part of the book series: M.D. Anderson Solid Tumor Oncology Series ((MDA,volume 5))

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Abstract

Desmoid tumours are rare and may occur spontaneously or in association with FAP (familial adenomatous polyposis). In both settings trauma as a trigger for growth initiation has been postulated. They differ in their predominant localisation, whereas differences in biological behaviour or response to therapeutic approaches have yet to be delineated. In all cases the tumour is frequently not recognized and treatment options are not being weighed thoroughly. Frequent debulking procedures lead to more aggressive growth and high morbidity and mortality. For the majority of desmoid tumours a less aggressive therapeutic approach may be more benefical in the long-term results, especially for desmoids occurring in the mesentery of FAP patients, that have already been subjected to colectomy.

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Authors and Affiliations

  1. HELIOS St. Josefs-Hospital Bochum-Linden, Axstr. 35, Bochum, 44879, Germany

    Gabriela Moeslein

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  1. Gabriela Moeslein
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Correspondence to Gabriela Moeslein .

Editor information

Editors and Affiliations

  1. M.D. Anderson Cancer Center, Surgical Oncology, The University of Texas, Holcombe Blvd. 1515, Houston, 77030, Texas, USA

    Miguel A. Rodriguez-Bigas

  2. Associate Professor of Surgery, Brazilian Registry of Inherited, Colorec, University of São Paulo Medical School, Sao Paulo, Brazil

    Raul Cutait

  3. M.D. Anderson Cancer Center, Gastroenterology, The University of Texas, Houston, 77030, Texas, USA

    Patrick M. Lynch

  4. Cancer Research UK London Research Insti, Molecular and Population Genetics Labora, London, United Kingdom

    Ian Tomlinson

  5. Medical Center, Gastroenterology, Leiden University, Leiden, 2333 AA, Netherlands

    Hans F.A. Vasen

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Moeslein, G. (2010). FAP-Associated Desmoid Tumours. In: Rodriguez-Bigas, M., Cutait, R., Lynch, P., Tomlinson, I., Vasen, H. (eds) Hereditary Colorectal Cancer. M.D. Anderson Solid Tumor Oncology Series, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6603-2_13

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  • DOI: https://doi.org/10.1007/978-1-4419-6603-2_13

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-6602-5

  • Online ISBN: 978-1-4419-6603-2

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