Neurostimulation Design from an Energy and Information Transfer Perspective

  • David A. Dinsmoor
  • Robert W. HockenJr
  • Wesley A. Santa
  • Jalpa S. Shah
  • Larry Tyler
  • Timothy J. Denison
Part of the Integrated Circuits and Systems book series (ICIR)


Neurostimulation—defined as electrical charge delivery for the purpose of affecting the behavior of nervous tissue—is one of the fastest growing applications in biomedical engineering. In the United States alone, neurostimulation products represented a $628 million market in 2006 with an expected annual growth rate of 20% [1]. Example applications include neurostimulation for pain control, incontinence, hearing loss, epilepsy and essential tremor. Even more exciting for engineers, researchers and venture capitalists are the nascent and under-developed applications of neurostimulation—particularly neurostimulation to restore function lost to neurological diseases or injury. At the heart of any such system is a circuit which drives neural tissue with electricity. An example radiograph showing the key elements of a neuromodulation system is shown in Fig. 13.1 these elements include the energy source, neurostimulation circuitry, mechanical packaging and stimulating electrodes. All neuromodulation systems have these general elements.


Deep Brain Stimulation Essential Tremor Charge Pump Coupling Capacitor Reference Resistor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • David A. Dinsmoor
    • 1
  • Robert W. HockenJr
    • 1
  • Wesley A. Santa
    • 1
  • Jalpa S. Shah
    • 1
  • Larry Tyler
    • 1
  • Timothy J. Denison
    • 2
  1. 1.Medtronic Neuromodulation Integrated Circuit TechnologyMinneapolisUSA
  2. 2.Medtronic Neuromodulation Integrated Circuit TechnologyColumbia HeightsUSA

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