Intraoperative Evaluation for Extracolonic Disease in Colon Cancer Patients

Chapter
Part of the Frozen Section Library book series (FROZEN, volume 4)

Abstract

Although radiographic studies usually provide accurate preoperative staging information in colorectal cancer patients, intraoperative frozen section evaluation of extracolonic tissues may be requested in order to confirm the diagnosis of a metastasis or ensure its complete resection. The liver represents the most common site of distant organ metastases from colorectal cancer. Several benign lesions may simulate liver metastases, most notably von Meyenberg complexes and bile duct hamartomas. Peritoneal carcinomatosis is also an important intraoperative finding that may alter the surgical management of colon cancer patients. A number of mimics of peritoneal carcinomatosis are encountered in the frozen section laboratory.

Keywords

Metastasis Liver Bile duct hamartoma Peritoneal carcinomatosis 

References

  1. 1.
    Cao CQ, Yan TD, Liauw W, Morris DL (2009) Comparison of optimally resected hepatectomy and peritonectomy patient with colorectal cancer metastasis. J Surg Oncol 100(7):529–533PubMedCrossRefGoogle Scholar
  2. 2.
    Rakha E, Ramaiah S, McGregor A (2006) Accuracy of frozen section in the diagnosis of liver mass lesions. J Clin Pathol 59:352–354PubMedCrossRefGoogle Scholar
  3. 3.
    Citak EC, Karadeniz C, Oguz A, Boyunaga O, Ekinci O, Okur V (2007) Nodular regenerative hyperplasia and focal nodular hyperplasia of the liver mimicking hepatic metastasis in children with solid tumors and a review of literature. Pediatr Hematol Oncol 24(4):281–289PubMedCrossRefGoogle Scholar
  4. 4.
    Kondi-Pafiti AI, Grapsa DS, Kairi-Vasilatou ED, Voros DK, Smyrniotis VE (2006) “Solitary necrotic nodule of the liver”: an enigmatic entity mimicking malignancy. Int J Gastrointest Cancer 37(23):74–78PubMedCrossRefGoogle Scholar
  5. 5.
    Kroncke TJ, Taupitz M, Kivelitz D, et al (2000) Multifocal nodular fatty infiltration of the liver mimicking metastatic disease on CT: imaging findings and diagnosis using MR imaging. Eur Radiol 10(7):1095–1100PubMedCrossRefGoogle Scholar
  6. 6.
    Ryan RS, Al-Hashimi H, Lee MJ (2001) Hepatic abscesses in elderly patients mimicking metastatic disease. Ir J Med Sci 170(4):251–253PubMedCrossRefGoogle Scholar
  7. 7.
    Yamashita Y, Shimada M, Taguchi K, et al (2000) Hepatic sclerosing hemangioma mimicking a metastatic liver tumor: report of a case. Surg Today 30(9):849–852PubMedCrossRefGoogle Scholar
  8. 8.
    Yoon KH, Yun KJ, Lee JM, Kim CG (2000) Solitary necrotic nodules of the liver mimicking hepatic metastases: report of two cases. Korean J Radiol 1(3):165–168PubMedCrossRefGoogle Scholar
  9. 9.
    Varban O, Levine EA, Stewart JH, McCoy TP, Shen P (2009) Outcomes associated with cytoreductive surgery and intraperitoneal hyperthermic chemotherapy in colorectal patients with peritoneal surface disease and hepatic metastases. Cancer 115(15):3427–3436PubMedCrossRefGoogle Scholar
  10. 10.
    DeHaas RJ, Wicherts DA, Adam R (2008) Resection of colorectal liver metastases with extrahepatic disease. Dig Surg 25(6):461–466CrossRefGoogle Scholar
  11. 11.
    Clement PB, Granai CO, Young RH, Scully RE (1994) Endometriosis with myxoid change. A case simulating pseudomyxoma peritonei. Am J Surg Pathol 18(8):849–853PubMedCrossRefGoogle Scholar
  12. 12.
    Hameed A, Jafri N, Copeland LJ, O’Toole RV (1996) Endometriosis with myxoid change simulating mucinous adenocarcinoma and pseudomyxoma peritonei. Gynecol Oncol 62(2):317–319PubMedCrossRefGoogle Scholar
  13. 13.
    Ozan H, Ozerkan K, Orhan A (2009) Peritoneal tuberculosis mimicking peritoneal carcinomatosis. Eur J Gynaecol Oncol 30(4):426–430PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Weill Medical College Cornell UniversityNew YorkUSA

Personalised recommendations