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Infectious Scleritis

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The Sclera

Abstract

Although immune-mediated diseases are the main disorders associated with scleritis, other, less common etiologies, such as infections, must also be considered. Infectious agents, such as bacteria, fungi, viruses, and parasites, may cause scleritis through a direct invasion or through an immune response. Infectious scleritis should be suspected in cases of indolent progressive scleral necrosis with suppuration, especially if the past and present history reveals an accidental trauma, chronic topical medication use (including corticosteroids), surgical procedures, or debilitating ocular or systemic disease; they also should be suspected if the review of systems reveal multisystem findings compatible with a systemic infection. In exogenous and endogenous infections, scrapings for smears and cultures must be obtained and fortified antimicrobial therapy, depending on smear results, must be initiated as soon as possible.

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Authors and Affiliations

  1. Clinical Institute of Ophthalmology, Hospital Clinic of Barcelona, Urgel 224, Barcelona, 08036, Spain

    Maite Sainz de la Maza MD, PhD (Clinical Associate Professor of Ophthalmology)

  2. Tauber Eye Center, 4400 Broadway, Suite 202, Kansas City, MO, 64111, USA

    Joseph Tauber MD

  3. Massachusetts Eye Research and Surgery Institution, Cambridge, MA, 02142, USA

    C. Stephen Foster MD (Professor of Ophthalmology Harvard Medical School)

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  1. Maite Sainz de la Maza MD, PhD
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de la Maza, M.S., Tauber, J., Foster, C.S. (2012). Infectious Scleritis. In: The Sclera. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6502-8_7

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