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Noninfectious Scleritis

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The Sclera

Abstract

Because scleritis may occur in association with a variety of noninfectious local and systemic disorders (autoimmune, dermatological, metabolic, and foreign body reactions), its presence must be regarded in relation to the larger picture of a patient’s general health. Scleritis is frequently seen in association with autoimmune vasculitic diseases that affect predominantly small- and medium-sized vessels, such as rheumatoid arthritis, granulomatosis with polyangiitis (Wegener), relapsing polychondritis, arthritis and inflammatory bowel disease, systemic lupus erythematosus, polyarteritis nodosa, psoriatic arthritis, Behçet’s disease, or Cogan’s disease; scleritis is less commonly found in association with autoimmune vasculitic diseases that affect predominantly large-sized arteries, such as reactive arthritis, ankylosing spondylitis, or giant-cell arteritis. Scleritis may also be associated with other diseases, such as atopy, rosacea, gout, or local foreign body reactions.

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Correspondence to Maite Sainz de la Maza MD, PhD .

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de la Maza, M.S., Tauber, J., Foster, C.S. (2012). Noninfectious Scleritis. In: The Sclera. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6502-8_6

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