Brain Imaging in Behavioral Medicine and Clinical Neuroscience: An Introduction

  • Ronald A. Cohen
  • Lawrence H. Sweet


We are living in a remarkable time in the history of neuroscience. A little over a century ago, neuropsychology had not yet emerged as a formal area of scientific inquiry, and knowledge regarding brain function was largely limited to pioneering studies of the effects of brain damage on cognitive functions. Demonstration by Broca and Wernicke of expressive and receptive aphasia associated with focal brain lesions resulted in an initial understanding of the functional neuroanatomy of language (Broca, Rev Prat 49(16):1725–1727, 1999; Geschwind, Wernicke’s Contribution to the Study of Aphasia, 1997), while observation of effects of frontal lobe damage in the famous case of Phineus Gage spurred initial speculation about the role of the frontal lobes in behavior and emotional control (Harlow, J Neuropsychiatry Clin Neurosci 11(2):281–283, 1999). This led to a steady increase in scientific research in the clinic and laboratory over the first half of the twentieth century to understand brain function, providing a foundation of knowledge for the field of Neuropsychology.


Single Photon Emission Compute Tomography Nicotine Dependence Behavioral Medicine Blood Oxygen Level Dependent Blood Oxygen Level Dependent Signal 
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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Psychiatry and Human Behavior and the Institute for Brain ScienceWarren Alpert Medical School of Brown UniversityProvidenceUSA

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