Separation and Characterization of Biomolecules Based on Macroscopic Properties
In Chapter 2 the importance of identifying the components in a system was introduced. A component may be distinguished because of certain characteristic properties that allow them to be separated from each other and then uniquely identified. Among the most useful macroscopic properties of a specific element within a system are its characteristic motions when subjected to either a constant or an accelerating force field. This often allows both separation and concurrent characterization. There are a variety of motions that are commonly encountered in biophysical separations. We will briefly describe several of these; first motion affected by normal, frictional, buoyant, and drag forces and then methods of inducing motion by means of applying acceleration forces.